Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 20/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14977694 | 0.89 | SYK (0.62) | SYK | |
| SCHEMBL14977422 | 0.87 | SYK (0.62) | SYK | |
| SCHEMBL1353737 | 0.81 | SYK (1.00) | SYK | |
| SCHEMBL1353731 | 0.81 | SYK (1.00) | SYK | |
| SCHEMBL14981671 | 0.79 | SYK (0.72) | SYK | |
| SCHEMBL16195129 | 0.79 | SYK (0.72) | SYK | |
| SCHEMBL1354473 | 0.79 | SYK (1.00) | SYK | |
| SCHEMBL1354470 | 0.79 | SYK (1.00) | SYK | |
| SCHEMBL14977488 | 0.78 | SYK (0.58) | SYK | |
| SCHEMBL16195339 | 0.78 | SYK (0.68) | SYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2782580-A1 | SELECTIVE KINASE INHIBITORS | Portola Pharmaceuticals, Inc. (US) | 2014-10-01 | — | — | EP | disclosed |
| WO-2013078468-A1 | SELECTIVE KINASE INHIBITORS | PORTOLA PHARMACEUTICALS, INC. (US) | 2013-05-30 | — | — | WO | disclosed |