SCHEMBL14977607

SCHEMBL14977607

CCCC(C)n1ccc2cc(O)ccc21

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BRD4 O60885 2/20 0.47
SLC2A1 P11166 1/20 0.44
KDM4E B2RXH2 1/20 0.43
MEN1 O00255 1/20 0.43
ALDH1A1 P00352 1/20 0.43
GAA P10253 1/20 0.43
KMT2A Q03164 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
SLC6A2 P23975 3/20 0.37
HTR2A P28223 3/20 0.33
HTR2C P28335 3/20 0.33
HTR1A P08908 2/20 0.33
ADRA2A P08913 2/20 0.33
ADRA2B P18089 2/20 0.33
ADRA2C P18825 2/20 0.33
HTR2B P41595 2/20 0.33
HTR1D P28221 1/20 0.33
HTR7 P34969 1/20 0.33
HTR4 Q13639 1/20 0.33
SLC6A4 P31645 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15024791 0.83 BRD4 (0.51) BRD4SLC2A1GAASLC6A2HTR2A
SCHEMBL21244767 0.80 KDM4E (0.39) BRD4KDM4EMEN1ALDH1A1GAA
SCHEMBL20037238 0.77 SLC6A2 (0.57) BRD4SLC2A1SLC6A2HTR2ASLC6A4
SCHEMBL14985318 0.77 BRD4 (0.46) BRD4SLC2A1HTR2C
SCHEMBL27620262 0.76 GAA (0.35) KDM4EMEN1ALDH1A1GAAKMT2A
SCHEMBL4463193 0.76 GAA (0.40) KDM4EMEN1ALDH1A1GAAKMT2A
SCHEMBL8845768 0.76 SLC6A2 (0.68) KDM4EMEN1ALDH1A1GAAKMT2A
SCHEMBL14977575 0.74 NPC1 (0.50) BRD4MEN1KMT2AHTR7
SCHEMBL3681424 0.74 GAA (0.40) KDM4EMEN1ALDH1A1GAAKMT2A
SCHEMBL2488326 0.74 ITGB3 (0.40) KDM4EMEN1ALDH1A1GAAKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9067886-B2 Compounds having semiconducting properties and related compositions and devices POLYERA CORPORATION (US) 2015-06-30 US disclosed
US-9067886-B2 Compounds having semiconducting properties and related compositions and devices POLYERA CORPORATION (US) 2015-06-30 US disclosed
US-9067886-B2 Compounds having semiconducting properties and related compositions and devices POLYERA CORPORATION (US) 2015-06-30 US disclosed
CN-104126235-A Compounds having semiconducting properties and related compositions and devices POLYERA CORP 2014-10-29 CN disclosed
EP-2782602-A1 METHOD FOR PREVENTION OF COLECTOMY Index Pharmaceuticals AB (SE) 2014-10-01 EP disclosed
US-20130146851-A1 Compounds Having Semiconducting Properties and Related Compositions and Devices POLYERA CORPORATION (US) 2013-06-13 US disclosed
US-20130146851-A1 Compounds Having Semiconducting Properties and Related Compositions and Devices POLYERA CORPORATION (US) 2013-06-13 US disclosed
US-20130146851-A1 Compounds Having Semiconducting Properties and Related Compositions and Devices POLYERA CORPORATION (US) 2013-06-13 US disclosed
WO-2013078407-A1 COMPOUNDS HAVING SEMICONDUCTING PROPERTIES AND RELATED COMPOSITIONS AND DEVICES POLYERA CORPORATION (US) 2013-05-30 WO disclosed
WO-2013078407-A1 COMPOUNDS HAVING SEMICONDUCTING PROPERTIES AND RELATED COMPOSITIONS AND DEVICES POLYERA CORPORATION (US) 2013-05-30 WO disclosed
WO-2013076262-A1 METHOD FOR PREVENTION OF COLECTOMY INDEX PHARMACEUTICALS AB (SE) 2013-05-30 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130146851-A1 Compounds Having Semiconducting Properties and Related Compositions and Devices NES, KCNN2, EPCAM BRD4 546/4885SLC2A1 445/4885KDM4E 3156/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.