Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.32 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 2/20 | 0.32 |
| ▸ | CA1 | P00915 | 2/20 | 0.32 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
| ▸ | CA7 | P43166 | 2/20 | 0.32 |
| ▸ | CA9 | Q16790 | 2/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.32 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.32 |
| ▸ | TUBB | P07437 | 1/20 | 0.32 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.32 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27619977 | 0.86 | DPP7 (0.32) | GAAALDH1A1ALOX15MTNR1AMTNR1B | |
| SCHEMBL27620024 | 0.81 | SRD5A2 (0.48) | MEN1KMT2ALMNAMAOB | |
| SCHEMBL3681424 | 0.77 | GAA (0.40) | GAAMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL14977607 | 0.76 | BRD4 (0.47) | GAAMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL2000119 | 0.74 | NR3C2 (0.39) | KMT2ACA12CA1CA2CA7 | |
| SCHEMBL2000984 | 0.74 | NR3C2 (0.39) | KMT2ACA12CA1CA2CA7 | |
| SCHEMBL27639166 | 0.74 | MTNR1A (0.46) | GAAKDM4EMTNR1AMTNR1B | |
| SCHEMBL27658305 | 0.73 | NTSR1 (0.42) | ALDH1A1KDM4ESMN1; SMN2HSP90AB1HPGD | |
| SCHEMBL21244767 | 0.72 | KDM4E (0.39) | GAAMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL2002647 | 0.72 | PTGS2 (0.38) | GAAMEN1KMT2AALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1751037-A | Sulfonamide derivatives as PPAR modulators | LILLY CO ELI (US) | 2006-03-22 | — | — | CN | disclosed |