Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 13/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.48 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14977772 | 0.92 | DHODH (0.60) | DHODHKMT2AGAASMN1; SMN2 | |
| SCHEMBL14985324 | 0.90 | DHODH (0.61) | DHODHKMT2AGAASMN1; SMN2NOD2 | |
| SCHEMBL14985323 | 0.90 | DHODH (0.55) | DHODHKMT2AGAASMN1; SMN2NOD2 | |
| SCHEMBL14977651 | 0.87 | DHODH (0.47) | DHODHKMT2ANOD2NOD1 | |
| SCHEMBL14977477 | 0.84 | DHODH (0.56) | DHODHKMT2AGAASMN1; SMN2 | |
| SCHEMBL18825171 | 0.84 | DHODH (0.78) | DHODHKMT2AGAASMN1; SMN2 | |
| SCHEMBL14977788 | 0.83 | DHODH (0.69) | DHODHKMT2AGAASMN1; SMN2 | |
| SCHEMBL14985285 | 0.82 | DHODH (0.54) | DHODHKMT2AGAASMN1; SMN2 | |
| SCHEMBL14977397 | 0.81 | DHODH (0.71) | DHODHKMT2AGAASMN1; SMN2 | |
| SCHEMBL14985308 | 0.80 | PKM (0.45) | DHODHKMT2AGAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013078413-A1 | MODULATORS OF LIPID STORAGE | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2013-05-30 | — | — | WO | disclosed |