Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | PDE6D | O43924 | 1/20 | 0.45 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.45 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.45 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.45 |
| ▸ | TPSAB1 | Q15661 | 3/20 | 0.45 |
| ▸ | F2 | P00734 | 2/20 | 0.45 |
| ▸ | PLG | P00747 | 2/20 | 0.45 |
| ▸ | CHI3L1 | P36222 | 1/20 | 0.44 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.44 |
| ▸ | LYPLA2 | O95372 | 1/20 | 0.43 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.43 |
| ▸ | DHODH | Q02127 | 5/20 | 0.43 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.43 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.43 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14977448 | 0.92 | DHODH (0.44) | PDE6DDHODHGAAKMT2ASMN1; SMN2 | |
| SCHEMBL14977653 | 0.80 | DHODH (0.60) | DHODHGAAKMT2ASMN1; SMN2 | |
| SCHEMBL14985324 | 0.77 | DHODH (0.61) | DHODHGAAKMT2ASMN1; SMN2 | |
| SCHEMBL14985323 | 0.77 | DHODH (0.55) | DHODHGAAKMT2ASMN1; SMN2 | |
| SCHEMBL13328914 | 0.74 | GBA1 (0.56) | PKMPDE6DPRSS1PRSS2PRSS3 | |
| SCHEMBL13328915 | 0.74 | GBA1 (0.56) | PKMPDE6DPRSS1PRSS2PRSS3 | |
| SCHEMBL10168530 | 0.73 | PKM (0.60) | PKMPDE6DPRSS1PRSS2PRSS3 | |
| SCHEMBL4401352 | 0.73 | PKM (0.60) | PKMPDE6DPRSS1PRSS2PRSS3 | |
| SCHEMBL16693779 | 0.73 | PKM (0.60) | PKMPDE6DPRSS1PRSS2PRSS3 | |
| SCHEMBL4160745 | 0.73 | PKM (0.59) | PKMPRSS1PRSS2PRSS3TPSAB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013078413-A1 | MODULATORS OF LIPID STORAGE | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2013-05-30 | — | — | WO | disclosed |