Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA5 | P22460 | 1/20 | 0.36 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.35 |
| ▸ | LPL | P06858 | 2/20 | 0.34 |
| ▸ | LIPG | Q9Y5X9 | 2/20 | 0.34 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | PGK1 | P00558 | 1/20 | 0.32 |
| ▸ | HTR3A | P46098 | 2/20 | 0.32 |
| ▸ | CCR2 | P41597 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | ESR1 | P03372 | 2/20 | 0.31 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | STK17B | O94768 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7893688 | 0.83 | ENPP2 (0.39) | ENPP2EPHX2ABCC9EGFRMAPT | |
| SCHEMBL29955343 | 0.83 | ENPP2 (0.39) | ENPP2EPHX2ABCC9EGFRMAPT | |
| SCHEMBL29954146 | 0.78 | TP53 (0.40) | ENPP2EPHX2MAPTTP53SMN1; SMN2 | |
| SCHEMBL7893158 | 0.78 | TP53 (0.40) | ENPP2EPHX2MAPTTP53SMN1; SMN2 | |
| SCHEMBL7375241 | 0.77 | KCNA5 (0.38) | KCNA5EPHX2MAPTPGK1HTR3A | |
| SCHEMBL29953328 | 0.75 | HTR3A (0.43) | ENPP2EPHX2ABCC9HTR3ASMN1; SMN2 | |
| SCHEMBL7897734 | 0.75 | HTR3A (0.43) | ENPP2EPHX2ABCC9HTR3ASMN1; SMN2 | |
| SCHEMBL17805164 | 0.73 | EPHX2 (0.36) | EPHX2ABCC9MAPTHTR3AESR1 | |
| SCHEMBL13370533 | 0.71 | ENPP2 (0.42) | ENPP2ESR1ESR2 | |
| SCHEMBL14748184 | 0.68 | HTR3A (0.47) | KCNA5EPHX2ABCC9HTR3AESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8476282-B2 | Benzoxazole kinase inhibitors and methods of use | INTELLIKINE LLC (US) | 2013-07-02 | — | — | US | disclosed |
| US-8450329-B2 | — | — | 2013-05-28 | — | — | US | disclosed |