Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 2/20 | 0.52 |
| ▸ | L3MBTL3 | Q96JM7 | 9/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 8/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | MBTD1 | Q05BQ5 | 2/20 | 0.32 |
| ▸ | TP53BP1 | Q12888 | 1/20 | 0.31 |
| ▸ | L3MBTL4 | Q8NA19 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14964734 | 0.86 | CHRM1 (0.53) | CHRM1L3MBTL3L3MBTL1HRH3KCNH2 | |
| SCHEMBL16217946 | 0.85 | CHRM1 (0.73) | CHRM1L3MBTL1ALDH1A1 | |
| SCHEMBL14964784 | 0.82 | CHRM1 (0.73) | CHRM1L3MBTL3L3MBTL1HRH3ALDH1A1 | |
| SCHEMBL17254480 | 0.82 | CHRM1 (0.73) | CHRM1L3MBTL3L3MBTL1HRH3ALDH1A1 | |
| SCHEMBL16217929 | 0.74 | CHRM1 (0.70) | CHRM1L3MBTL1ALDH1A1 | |
| SCHEMBL14978786 | 0.74 | CHRM1 (0.70) | CHRM1L3MBTL1ALDH1A1MEN1KMT2A | |
| SCHEMBL2039482 | 0.73 | L3MBTL3 (0.39) | CHRM1L3MBTL3L3MBTL1HRH3KCNH2 | |
| SCHEMBL16210465 | 0.73 | CHRM1 (0.55) | CHRM1HRH3ALDH1A1MEN1KMT2A | |
| SCHEMBL14964764 | 0.72 | CHRM1 (0.43) | CHRM1L3MBTL3L3MBTL1HRH3KCNH2 | |
| SCHEMBL14978787 | 0.72 | CHRM1 (0.67) | CHRM1L3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013072705-A1 | MUSCARINIC M1 RECEPTOR AGONISTS | HEPTARES THERAPEUTICS LIMITED (GB) | 2013-05-23 | — | — | WO | disclosed |