Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 2/20 | 0.46 |
| ▸ | LPL | P06858 | 2/20 | 0.42 |
| ▸ | LIPG | Q9Y5X9 | 2/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.42 |
| ▸ | SCN5A | Q14524 | 3/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.40 |
| ▸ | PPARG | P37231 | 2/20 | 0.40 |
| ▸ | PPARA | Q07869 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL612555 | 0.99 | KIF11 (0.45) | KIF11LPLLIPGTAAR1SCN5A | |
| SCHEMBL612976 | 0.96 | KIF11 (0.47) | KIF11LPLLIPGTAAR1PPARG | |
| SCHEMBL10237600 | 0.93 | KIF11 (0.49) | KIF11LPLLIPGTAAR1PPARG | |
| SCHEMBL10236374 | 0.91 | LPL (0.46) | LPLLIPGSCN5ASCN9APPARG | |
| SCHEMBL10235741 | 0.90 | LPL (0.48) | LPLLIPGSCN5ASCN9APPARG | |
| SCHEMBL10235736 | 0.87 | LPL (0.44) | KIF11LPLLIPGPPARGPPARA | |
| SCHEMBL13959780 | 0.83 | KIF11 (0.48) | KIF11LPLLIPGTAAR1 | |
| SCHEMBL3859063 | 0.82 | LPL (0.40) | KIF11LPLLIPGPPARGPPARA | |
| SCHEMBL14642898 | 0.81 | KIF11 (0.49) | KIF11LPLLIPGTAAR1 | |
| SCHEMBL4948885 | 0.81 | TAAR1 (0.50) | KIF11TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8450527-B2 | Amine derivative compounds for treating ophthalmic diseases and disorders | ACUCELA INC. (US) | 2013-05-28 | — | — | US | disclosed |