Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.63 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.34 |
| ▸ | CA12 | O43570 | 3/20 | 0.33 |
| ▸ | CA6 | P23280 | 3/20 | 0.33 |
| ▸ | CA7 | P43166 | 3/20 | 0.33 |
| ▸ | CA9 | Q16790 | 3/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.33 |
| ▸ | CA5B | Q9Y2D0 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
| ▸ | CA3 | P07451 | 2/20 | 0.32 |
| ▸ | CA4 | P22748 | 2/20 | 0.32 |
| ▸ | CA5A | P35218 | 2/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16504257 | 0.92 | ACE2 (0.52) | ACE2CYP2C9CYP2C19ALOX15CA12 | |
| SCHEMBL14980602 | 0.90 | ACE2 (0.50) | ACE2ALOX15SIGMAR1 | |
| SCHEMBL16504255 | 0.86 | ACE2 (0.46) | ACE2CYP2C9CYP2C19MEN1KMT2A | |
| SCHEMBL16078967 | 0.86 | ACE2 (0.42) | ACE2SIGMAR1 | |
| SCHEMBL14980601 | 0.82 | ALOX15 (0.42) | ACE2ALOX15ALDH1A1KDM4ESIGMAR1 | |
| SCHEMBL16920221 | 0.82 | ACE2 (0.79) | ACE2CYP2C9CYP2C19ALOX15CA12 | |
| SCHEMBL19071702 | 0.81 | ACE2 (0.66) | ACE2CYP2C9CYP2C19ALOX15CA12 | |
| SCHEMBL16504256 | 0.80 | ACE2 (0.76) | ACE2CYP2C9CYP2C19ALOX15CA12 | |
| SCHEMBL1263735 | 0.80 | CYP2C19 (0.50) | ACE2CYP2C9CYP2C19ALOX15CA12 | |
| SCHEMBL12921297 | 0.80 | ACE2 (1.00) | ACE2CYP2C9CYP2C19ALOX15CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8450298-B2 | Aminoalcohol lipidoids and uses thereof | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2013-05-28 | — | — | US | disclosed |