Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14980600 | 0.90 | ACE2 (0.63) | ACE2SIGMAR1ALOX15 | |
| SCHEMBL16078967 | 0.90 | ACE2 (0.42) | ACE2SIGMAR1 | |
| SCHEMBL14980601 | 0.87 | ALOX15 (0.42) | ACE2SIGMAR1ALOX15 | |
| SCHEMBL16075890 | 0.83 | KDM4E (0.37) | ACE2 | |
| SCHEMBL14980599 | 0.83 | ALOX15 (0.50) | ACE2SIGMAR1ALOX15 | |
| SCHEMBL16504257 | 0.83 | ACE2 (0.52) | ACE2SIGMAR1ALOX15 | |
| SCHEMBL2748225 | 0.81 | CYP2C9 (0.37) | ALOX15 | |
| SCHEMBL16920221 | 0.79 | ACE2 (0.79) | ACE2SIGMAR1ALOX15 | |
| SCHEMBL29860788 | 0.78 | ACE2 (0.50) | ACE2SIGMAR1ALOX15 | |
| SCHEMBL16078964 | 0.78 | ACE2 (0.63) | ACE2SIGMAR1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8450298-B2 | Aminoalcohol lipidoids and uses thereof | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2013-05-28 | — | — | US | disclosed |