Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 9/20 | 0.42 |
| ▸ | ANPEP | P15144 | 2/20 | 0.39 |
| ▸ | KDM1A | O60341 | 1/20 | 0.39 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.39 |
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | DAO | P14920 | 1/20 | 0.35 |
| ▸ | PDE2A | O00408 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14980642 | 0.86 | ANPEP (0.39) | ANPEPENPEPPDE2A | |
| SCHEMBL14980670 | 0.84 | KIF11 (0.43) | KIF11KDM1ASLC7A5FFAR1DAO | |
| SCHEMBL16649703 | 0.84 | SLC7A5 (0.45) | KIF11KDM1ASLC7A5FFAR1DAO | |
| SCHEMBL4020708 | 0.83 | KIF11 (0.42) | KIF11KDM1ASLC7A5FFAR1PDE2A | |
| SCHEMBL15157447 | 0.83 | KIF11 (0.42) | KIF11KDM1ASLC7A5FFAR1PDE2A | |
| SCHEMBL15157706 | 0.83 | KIF11 (0.42) | KIF11KDM1ASLC7A5FFAR1PDE2A | |
| SCHEMBL14981124 | 0.81 | ANPEP (0.38) | ANPEPENPEPDAOPDE2A | |
| SCHEMBL12497284 | 0.80 | KIF11 (0.44) | KIF11KDM1ASLC7A5FFAR1PDE2A | |
| SCHEMBL12497573 | 0.80 | KIF11 (0.44) | KIF11KDM1ASLC7A5FFAR1PDE2A | |
| SCHEMBL15512187 | 0.80 | KIF11 (0.44) | KIF11KDM1ASLC7A5FFAR1PDE2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2634191-A1 | Process for preparing derivatives of thienopyrimidinedione | Glenmark Pharmaceuticals S.A. (CH) | 2013-09-04 | — | — | EP | disclosed |
| EP-2411395-B1 | FUROPYRIMIDINEDIONE DERIVATIVES AS TRPA1 MODULATORS | GLENMARK PHARMACEUTICALS SA (CH) | 2013-05-29 | — | — | EP | disclosed |
| EP-2411397-B1 | ISOTHIAZOLO-PYRIMIDINEDIONE DERIVATIVES AS TRPA1 MODULATORS | GLENMARK PHARMACEUTICALS SA (CH) | 2013-05-29 | — | — | EP | disclosed |
| EP-2411396-B1 | THIENOPYRIMIDINEDIONE DERIVATIVES AS TRPA1 MODULATORS | GLENMARK PHARMACEUTICALS SA (CH) | 2013-05-29 | — | — | EP | disclosed |