Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.34 |
| ▸ | EP300 | Q09472 | 1/20 | 0.34 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.34 |
| ▸ | PLK1 | P53350 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14980671 | 0.87 | USP2 (0.37) | USP2BRD4BRPF1EP300CREBBP | |
| SCHEMBL15241099 | 0.64 | TBXA2R (0.30) | — | |
| SCHEMBL14981143 | 0.62 | USP2 (0.30) | USP2 | |
| SCHEMBL13189445 | 0.59 | APEX1 (0.38) | — | |
| SCHEMBL24415030 | 0.59 | USP2 (0.42) | USP2BRD4BRPF1EP300CREBBP | |
| SCHEMBL9097369 | 0.57 | ALDH1A1 (0.36) | — | |
| SCHEMBL29532612 | 0.56 | GRIA2 (0.38) | — | |
| SCHEMBL10713707 | 0.55 | ALDH1A1 (0.41) | USP2 | |
| SCHEMBL9880895 | 0.54 | HPGD (0.50) | USP2 | |
| SCHEMBL11744319 | 0.52 | AKR1B1 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2411396-B1 | THIENOPYRIMIDINEDIONE DERIVATIVES AS TRPA1 MODULATORS | GLENMARK PHARMACEUTICALS SA (CH) | 2013-05-29 | — | — | EP | disclosed |