Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | CASP3 | P42574 | 1/20 | 0.46 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.46 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.46 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.46 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | PARP1 | P09874 | 1/20 | 0.45 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.45 |
| ▸ | PARP4 | Q9UKK3 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3315274 | 0.88 | MAPK1 (0.45) | NPC1RAB9ACASP3SENP8SENP7 | |
| SCHEMBL17296893 | 0.86 | ATM (0.53) | NPC1RAB9ACASP3SENP8SENP7 | |
| SCHEMBL14980935 | 0.84 | PLK1 (0.44) | NPC1RAB9AMAPK1POLBATM | |
| SCHEMBL13398104 | 0.84 | POLB (0.43) | NPC1RAB9AMAPK1POLBATM | |
| SCHEMBL3315409 | 0.83 | ALDH1A1 (0.47) | POLBALDH1A1CNR2EPHX2 | |
| SCHEMBL14980957 | 0.83 | CNR2 (0.39) | PARP1POLBL3MBTL1ALDH1A1MAPT | |
| SCHEMBL13416786 | 0.82 | MAPK1 (0.40) | NPC1RAB9ACASP3SENP8SENP7 | |
| SCHEMBL3318434 | 0.82 | SMN1; SMN2 (0.47) | NPC1RAB9ACASP3SENP8SENP7 | |
| SCHEMBL17296896 | 0.81 | ALDH1A1 (0.54) | POLBL3MBTL1ALDH1A1MAPT | |
| SCHEMBL13398019 | 0.81 | SLC6A4 (0.44) | MAPK1POLBALDH1A1EPHX2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9199934-B2 | Alpha-hydroxyketones | BASF SE (DE) | 2015-12-01 | — | — | US | disclosed |
| EP-2129659-B1 | ALPHA-HYDROXYKETONES | BASF SE (DE) | 2013-05-29 | — | — | EP | disclosed |