Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLK1 | P53350 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17296893 | 0.87 | ATM (0.53) | SLC6A4SLC6A3EPHX2ATML3MBTL1 | |
| SCHEMBL13398104 | 0.86 | POLB (0.43) | SLC6A4SLC6A3EPHX2ATML3MBTL1 | |
| SCHEMBL14980937 | 0.85 | POLB (0.42) | SLC6A4SLC6A3EPHX2ATML3MBTL1 | |
| SCHEMBL3315274 | 0.85 | MAPK1 (0.45) | SLC6A4SLC6A3EPHX2ATML3MBTL1 | |
| SCHEMBL14980950 | 0.85 | ALDH1A1 (0.39) | SLC6A3EPHX2ALDH1A1MAPTNPC1 | |
| SCHEMBL14980948 | 0.84 | NPC1 (0.46) | SLC6A4SLC6A3EPHX2ATML3MBTL1 | |
| SCHEMBL3316993 | 0.83 | NPC1 (0.44) | SLC6A4SLC6A3EPHX2ALDH1A1NPC1 | |
| SCHEMBL3318810 | 0.83 | ALDH1A1 (0.47) | L3MBTL1ALDH1A1NPC1RAB9AHPGD | |
| SCHEMBL13398117 | 0.83 | GAA (0.47) | SLC6A4SLC6A3EPHX2L3MBTL1MAPK1 | |
| SCHEMBL3314282 | 0.82 | ALDH1A1 (0.44) | ALDH1A1NPC1RAB9AHPGDPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2129659-B1 | ALPHA-HYDROXYKETONES | BASF SE (DE) | 2013-05-29 | — | — | EP | disclosed |