Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | FKBP1A | P62942 | 2/20 | 0.40 |
| ▸ | FKBP4 | Q02790 | 1/20 | 0.40 |
| ▸ | FKBP5 | Q13451 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.39 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3318260 | 0.93 | CHRM2 (0.45) | POLBFKBP1AFKBP4FKBP5ATM | |
| SCHEMBL13397953 | 0.91 | FKBP1A (0.40) | FKBP1AFKBP4FKBP5ATML3MBTL1 | |
| SCHEMBL3314610 | 0.91 | ATM (0.39) | POLBFKBP1AFKBP4FKBP5ATM | |
| SCHEMBL3315534 | 0.89 | CHRM2 (0.42) | POLBFKBP1AFKBP4FKBP5ATM | |
| SCHEMBL3320618 | 0.89 | CHRM2 (0.42) | POLBFKBP1AFKBP4FKBP5ATM | |
| SCHEMBL3318434 | 0.88 | SMN1; SMN2 (0.47) | POLBATML3MBTL1ALDH1A1NPC1 | |
| SCHEMBL3315532 | 0.88 | FKBP1A (0.37) | POLBFKBP1AFKBP4FKBP5ATM | |
| SCHEMBL3315191 | 0.87 | FKBP1A (0.38) | FKBP1AFKBP4FKBP5ATML3MBTL1 | |
| SCHEMBL17296893 | 0.85 | ATM (0.53) | POLBATML3MBTL1ALDH1A1NPC1 | |
| SCHEMBL3314809 | 0.84 | ADRB2 (0.40) | POLBATML3MBTL1ALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2129659-B1 | ALPHA-HYDROXYKETONES | BASF SE (DE) | 2013-05-29 | — | — | EP | disclosed |