SCHEMBL14980966

SCHEMBL14980966

O=C(Oc1ccc(-c2ccc(F)cc2)cc1)c1ccc(O)cc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SENP1 Q9P0U3 1/20 0.53
KMT2A Q03164 4/20 0.51
MAPT P10636 2/20 0.51
MEN1 O00255 2/20 0.50
ATM Q13315 1/20 0.50
BCL2L1 Q07817 1/20 0.48
BAD Q92934 1/20 0.48
KDM4E B2RXH2 1/20 0.46
LMNA P02545 1/20 0.46
HSD17B10 Q99714 1/20 0.46
PARP10 Q53GL7 1/20 0.45
HSD17B1 P14061 1/20 0.44
CA12 O43570 1/20 0.44
CA1 P00915 1/20 0.44
CA2 P00918 1/20 0.44
CA7 P43166 1/20 0.44
CA9 Q16790 1/20 0.44
CA14 Q9ULX7 1/20 0.44
F2 P00734 1/20 0.44
PRSS1 P07477 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14145708 0.95 KMT2A (0.54) SENP1KMT2AMAPTMEN1ATM
SCHEMBL11311551 0.95 KMT2A (0.54) SENP1KMT2AMAPTMEN1ATM
SCHEMBL532901 0.95 KMT2A (0.54) SENP1KMT2AMAPTMEN1ATM
SCHEMBL14640391 0.95 KMT2A (0.54) SENP1KMT2AMAPTMEN1ATM
SCHEMBL768517 0.91 SENP1 (0.61) SENP1KMT2AMAPTMEN1KDM4E
SCHEMBL20938271 0.91 SENP1 (0.61) SENP1KMT2AMAPTMEN1KDM4E
SCHEMBL12711658 0.91 SENP1 (0.61) SENP1KMT2AMAPTMEN1KDM4E
SCHEMBL777651 0.91 SENP1 (0.61) SENP1KMT2AMAPTMEN1KDM4E
SCHEMBL17826635 0.91 SENP1 (0.61) SENP1KMT2AMAPTMEN1KDM4E
SCHEMBL2838573 0.87 KMT2A (0.61) KMT2AMAPTMEN1ATMKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2119701-B1 POLYMERIZABLE OPTICALLY-ACTIVE COMPOUND, AND POLYMERIZABLE COMPOSITION COMPRISING THE POLYMERIZABLE OPTICALLY-ACTIVE COMPOUND ADEKA CORP (JP) 2013-05-29 EP disclosed