Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 4/20 | 0.40 |
| ▸ | CACNA1G | O43497 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.39 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.38 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.38 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CKS1B | P61024 | 1/20 | 0.38 |
| ▸ | SKP1 | P63208 | 1/20 | 0.38 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21023138 | 0.84 | L3MBTL1 (0.50) | SIGMAR1CYP3A4NPSR1IDO1 | |
| SCHEMBL14985092 | 0.81 | DRD2 (0.39) | DRD2TDP1SIGMAR1CYP3A4CKS1B | |
| SCHEMBL14974018 | 0.80 | CKS1B (0.40) | DRD2TDP1SIGMAR1CYP3A4CKS1B | |
| SCHEMBL14974020 | 0.80 | CKS1B (0.40) | DRD2TDP1SIGMAR1CYP3A4CKS1B | |
| SCHEMBL14985020 | 0.80 | DRD2 (0.40) | DRD2CACNA1GTDP1CYP3A4CKS1B | |
| SCHEMBL14985081 | 0.80 | DRD2 (0.40) | DRD2CACNA1GTDP1CYP3A4CKS1B | |
| SCHEMBL14985103 | 0.80 | DRD2 (0.40) | DRD2CACNA1GTDP1CYP3A4CKS1B | |
| SCHEMBL14985021 | 0.80 | DRD2 (0.40) | DRD2CACNA1GTDP1CYP3A4CKS1B | |
| SCHEMBL14985095 | 0.79 | MAPT (0.40) | DRD2TDP1CKS1BSKP1SKP2 | |
| SCHEMBL14981897 | 0.76 | HDAC3 (0.40) | LMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8735622-B2 | Histone demethylase inhibitors and methods for using the same | THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE (US) | 2014-05-27 | — | — | US | disclosed |
| US-20130137720-A1 | HISTONE DEMETHYLASE INHIBITORS AND METHODS FOR USING THE SAME | The Regents of the University of Colorado, a body corporated (US) | 2013-05-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130137720-A1 | HISTONE DEMETHYLASE INHIBITORS AND METHODS FOR USING THE SAME | KDM1A, KDM3A, KDM7A | DRD2 4512/4885CACNA1G 3503/4885LMNA 641/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.