Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | CASP3 | P42574 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.46 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.46 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31697314 | 1.00 | KDM4E (0.50) | KDM4ETSHRLMNANPC1RAB9A | |
| SCHEMBL5317857 | 0.93 | KDM4E (0.53) | KDM4ETSHRLMNANPC1RAB9A | |
| SCHEMBL5263472 | 0.88 | KDM4E (0.49) | KDM4ETSHRLMNANPC1RAB9A | |
| SCHEMBL3995268 | 0.87 | KDM4E (0.53) | KDM4ETSHRLMNANPC1RAB9A | |
| SCHEMBL24834467 | 0.86 | KDM4E (0.48) | KDM4ETSHRALDH1A1NPSR1CA12 | |
| SCHEMBL28944494 | 0.86 | KDM4E (0.48) | KDM4ETSHRNPC1RAB9AALDH1A1 | |
| SCHEMBL4192553 | 0.86 | KDM4E (0.58) | KDM4ETSHRLMNANPC1RAB9A | |
| SCHEMBL29827383 | 0.86 | KDM4E (0.48) | KDM4ETSHRNPC1RAB9AALDH1A1 | |
| SCHEMBL9588785 | 0.85 | KDM4E (0.47) | KDM4ETSHRLMNAALDH1A1HPGD | |
| SCHEMBL6216482 | 0.85 | KDM4E (0.47) | KDM4ETSHRNPC1RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 56 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12441703-B2 | Carboxamides as modulators of sodium channels | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2025-10-14 | — | — | US | disclosed |
| CN-115232008-B | Compound, preparation method thereof and application of compound in preparation of fluroxypyr intermediate | 山东潍坊润丰化工股份有限公司 | 2024-05-17 | — | — | CN | disclosed |
| US-20240010605-A1 | COMPOUND, PREPARATION METHOD THEREFOR AND APPLICATION OF COMPOUND IN PREPARATION OF BICYCLOPYRONE INTERMEDIATE | SHANDONG WEIFANG RAINBOW CHEMICAL CO.,LTD (CN) | 2024-01-11 | — | — | US | disclosed |
| WO-2023237027-A1 | COMPOUND, METHOD FOR PREPARING SAME, AND USE THEREOF IN PREPARING BICYCLOPYRONE INTERMEDIATE | 山东潍坊润丰化工股份有限公司 | 2023-12-14 | — | — | WO | disclosed |
| US-20230062053-A1 | CARBOXAMIDES AS MODULATORS OF SODIUM CHANNELS | VERTEX PHARMACEUTICALS INCORPORATED | 2023-03-02 | — | — | US | disclosed |
| US-20230062053-A1 | CARBOXAMIDES AS MODULATORS OF SODIUM CHANNELS | VERTEX PHARMACEUTICALS INCORPORATED | 2023-03-02 | — | — | US | disclosed |
| CN-115232008-A | Compound, preparation method thereof and application of compound in preparation of fluroxypyr intermediate | 山东潍坊润丰化工股份有限公司 | 2022-10-25 | — | — | CN | disclosed |
| CN-114716320-B | Compound, preparation method thereof and application of compound in preparation of fluroxypyr intermediate | 山东潍坊润丰化工股份有限公司 | 2022-09-27 | — | — | CN | disclosed |
| CN-114716320-A | Compound, preparation method thereof and application of compound in preparation of fluroxypyr intermediate | 山东潍坊润丰化工股份有限公司 | 2022-07-08 | — | — | CN | disclosed |
| EP-2903991-B1 | ANTI-FIBROTIC PYRIDINONES | INTERMUNE INC (US) | 2020-09-16 | — | — | EP | disclosed |
| WO-2007071900-A1 | NOVEL HERBICIDES | SYNGENTA LIMITED (GB) | 2007-06-28 | — | — | WO | disclosed |
| EP-1789401-A1 | ISOXAZOLINE DERIVATIVES AND THEIR USE AS HERBICIDES | Syngenta Limited (GB) | 2007-05-30 | — | — | EP | disclosed |
| EP-1286985-B1 | SUBSTITUTED PYRIDINE HERBICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2006-06-21 | — | — | EP | disclosed |
| WO-2006059103-A2 | PYRIDINE BASED COMPOUNDS USEFUL AS INTERMEDIATES FOR PHARMACEUTICAL OR AGRICULTURAL END-PRODUCTS | PEAKDALE MOLECULAR LIMITED (GB) | 2006-06-08 | — | — | WO | disclosed |
| WO-2006024820-A1 | ISOXAZOLINE DERIVATIVES AND THEIR USE AS HERBICIDES | SYNGENTA LIMITED (GB) | 2006-03-09 | — | — | WO | disclosed |
| EP-1574510-A1 | Substituted pyridine herbicides | Syngenta Participations AG (CH) | 2005-09-14 | — | — | EP | disclosed |
| US-6838564-B2 | Substituted pyridine herbicides | SYNGENTA CROP PROTECTION, INC. (US) | 2005-01-04 | — | — | US | disclosed |
| US-20040097729-A1 | Substituted pyridine herbicides | SYNGENTA CROP PROTECTION, INC. | 2004-05-20 | — | — | US | disclosed |
| EP-1286985-A1 | SUBSTITUTED PYRIDINE HERBICIDES | Syngenta Participations AG (CH) | 2003-03-05 | — | — | EP | disclosed |
| WO-2001094339-A1 | SUBSTITUTED PYRIDINE HERBICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2001-12-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12441703-B2 | Carboxamides as modulators of sodium channels | TRPV1, SCN2A, SCN10A | KDM4E 1582/4885TSHR 3163/4885LMNA 2874/4885 |
| US-20040097729-A1 | Substituted pyridine herbicides | DDT, CYP1A1, CYP1B1 | KDM4E 917/4885TSHR 1642/4885LMNA 4198/4885 |
| US-20230062053-A1 | CARBOXAMIDES AS MODULATORS OF SODIUM CHANNELS | TRPV1, SCN2A, SCN10A | KDM4E 1582/4885TSHR 3163/4885LMNA 2874/4885 |
| US-20240010605-A1 | COMPOUND, PREPARATION METHOD THEREFOR AND APPLICATION OF COMPOUND IN PREPARATION OF BICYCLOPYRONE INTERMEDIATE | WEE1, WEE2, CYP4F11 | KDM4E 4226/4885TSHR 4450/4885LMNA 1846/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.