Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | SYK | P43405 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | CASP7 | P55210 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1498542 | 0.85 | KDM4E (0.50) | KDM4ETSHRNPSR1ALDH1A1CA12 | |
| SCHEMBL31697314 | 0.85 | KDM4E (0.50) | KDM4ETSHRNPSR1ALDH1A1CA12 | |
| SCHEMBL1498432 | 0.84 | KDM4E (0.46) | KDM4ETSHRMAPTNPSR1ALDH1A1 | |
| SCHEMBL24834467 | 0.84 | KDM4E (0.48) | KDM4ETSHRMAPTNPSR1ALDH1A1 | |
| SCHEMBL4192553 | 0.84 | KDM4E (0.58) | KDM4ETSHRMAPTNPSR1ALDH1A1 | |
| SCHEMBL28944494 | 0.84 | KDM4E (0.48) | KDM4ETSHRMAPTNPSR1ALDH1A1 | |
| SCHEMBL29827383 | 0.84 | KDM4E (0.48) | KDM4ETSHRMAPTNPSR1ALDH1A1 | |
| SCHEMBL124080 | 0.83 | TUBB4A (0.53) | NPSR1SMN1; SMN2CA12CA1CA2 | |
| SCHEMBL1375048 | 0.82 | KDM4E (0.53) | KDM4ETSHRMAPTNPSR1ALDH1A1 | |
| SCHEMBL9588785 | 0.82 | KDM4E (0.47) | KDM4ETSHRMAPTNPSR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240360117-A1 | BENZODIAZEPINE DERIVATIVES AS RSV INHIBITORS | ENANTA PHARM INC (US) | 2024-10-31 | — | — | US | disclosed |
| CN-113710276-B | Benzodiazepine derivatives as RSV inhibitors | 英安塔制药有限公司 | 2024-03-29 | — | — | CN | disclosed |
| US-11912695-B2 | Benzodiazepine derivatives as RSV inhibitors | ENANTA PHARMACEUTICALS, INC. (US) | 2024-02-27 | — | — | US | disclosed |
| US-20230103791-A1 | 2,3-DIHYDROQUINAZOLIN COMPOUNDS AS NAV1.8 INHIBITORS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2023-04-06 | — | — | US | disclosed |
| US-20220227746-A1 | BENZODIAZEPINE DERIVATIVES AS RSV INHIBITORS | ENANTA PHARM INC (US) | 2022-07-21 | — | — | US | disclosed |
| US-11254664-B2 | Benzodiazepine derivatives as RSV inhibitors | ENANTA PHARMACEUTICALS, INC. (US) | 2022-02-22 | — | — | US | disclosed |
| EP-3941525-A1 | BENZODIAZEPINE DERIVATIVES AS RSV INHIBITORS | Enanta Pharmaceuticals, Inc. (US) | 2022-01-26 | — | — | EP | disclosed |
| CN-113710276-A | Benzodiazepine derivatives as RSV inhibitors | 英安塔制药有限公司 | 2021-11-26 | — | — | CN | disclosed |
| WO-2020261114-A1 | 2,3-DIHYDROQUINAZOLIN COMPOUNDS AS NAV1.8 INHIBITORS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2020-12-30 | — | — | WO | disclosed |
| WO-2020190935-A1 | BENZODIAZEPINE DERIVATIVES AS RSV INHIBITORS | ENANTA PHARMACEUTICALS, INC. (US) | 2020-09-24 | — | — | WO | disclosed |
| US-20200299286-A1 | BENZODIAZEPINE DERIVATIVES AS RSV INHIBITORS | ENANTA PHARMACEUTICALS, INC. | 2020-09-24 | — | — | US | disclosed |
| EP-1140845-B1 | SUSBSTITUTED PYRIDINE HERBICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2005-02-23 | — | — | EP | disclosed |
| US-6673938-B1 | Substituted pyridine herbicides | SYNGENTA PARTICIPATIONS AG (CH) | 2004-01-06 | — | — | US | disclosed |
| US-6534445-B1 | Pyridine ketones for controlling weeds | SYNGENTA PARTICIPATIONS AG (CH) | 2003-03-18 | — | — | US | disclosed |
| US-20030040437-A1 | Substituted pyridine herbicides | SYNGENTA PARTICIPATIONS AG (CH) | 2003-02-27 | — | — | US | disclosed |
| EP-1140845-A1 | SUSBSTITUTED PYRIDINE HERBICIDES | Syngenta Participations AG (CH) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000039094-A1 | SUBSTITUTED PYRIDINE HERBICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2000-07-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11254664-B2 | Benzodiazepine derivatives as RSV inhibitors | GABRA5, GABRA1, GABBR2 | KDM4E 1198/4885TSHR 1396/4885MAPT 2157/4885 |
| US-11912695-B2 | Benzodiazepine derivatives as RSV inhibitors | GABRA5, GABRA1, GABBR2 | KDM4E 1198/4885TSHR 1396/4885MAPT 2157/4885 |
| US-20230103791-A1 | 2,3-DIHYDROQUINAZOLIN COMPOUNDS AS NAV1.8 INHIBITORS | SCN8A, SCN1A, SCN1B | KDM4E 3392/4885TSHR 2555/4885MAPT 215/4885 |
| US-20030040437-A1 | Substituted pyridine herbicides | DDT, CYP1A1, CYP1B1 | KDM4E 2318/4885TSHR 1093/4885MAPT 158/4885 |
| US-20240360117-A1 | BENZODIAZEPINE DERIVATIVES AS RSV INHIBITORS | GABRA5, GABRA1, GABBR2 | KDM4E 1198/4885TSHR 1396/4885MAPT 2157/4885 |
| US-20220227746-A1 | BENZODIAZEPINE DERIVATIVES AS RSV INHIBITORS | GABRA5, GABRA1, GABBR2 | KDM4E 1198/4885TSHR 1396/4885MAPT 2157/4885 |
| US-20200299286-A1 | BENZODIAZEPINE DERIVATIVES AS RSV INHIBITORS | GABRA5, GABRA1, GABBR2 | KDM4E 1198/4885TSHR 1396/4885MAPT 2157/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.