Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 10/20 | 0.49 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | CTSS | P25774 | 2/20 | 0.41 |
| ▸ | CTSL | P07711 | 1/20 | 0.40 |
| ▸ | DPP4 | P27487 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3599903 | 1.00 | REN (0.49) | RENCPB2HTTCTSSCTSL | |
| SCHEMBL1867207 | 0.89 | CTSS (0.54) | RENCTSSCTSLSMN1; SMN2 | |
| SCHEMBL5509776 | 0.86 | HTT (0.45) | RENCPB2HTTCTSSCTSL | |
| SCHEMBL5505421 | 0.86 | HTT (0.45) | RENCPB2HTTCTSSCTSL | |
| SCHEMBL5503829 | 0.82 | REN (0.52) | REN | |
| SCHEMBL5505794 | 0.82 | REN (0.52) | REN | |
| SCHEMBL1866281 | 0.82 | REN (0.52) | REN | |
| SCHEMBL1865703 | 0.82 | REN (0.52) | REN | |
| SCHEMBL5509831 | 0.82 | REN (0.52) | REN | |
| SCHEMBL3608717 | 0.81 | KDM4E (0.44) | RENHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8455521-B2 | Diaminoalkane aspartic protease inhibitors | VITAE PHARMACEUTICALS, INC. (US) | 2013-06-04 | — | — | US | disclosed |