Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.52 |
| ▸ | EYA2 | O00167 | 1/20 | 0.52 |
| ▸ | APP | P05067 | 1/20 | 0.52 |
| ▸ | ACE | P12821 | 1/20 | 0.52 |
| ▸ | BLM | P54132 | 3/20 | 0.50 |
| ▸ | PMP22 | Q01453 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.50 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.50 |
| ▸ | DRD1 | P21728 | 1/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.50 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.50 |
| ▸ | DRD3 | P35462 | 1/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.50 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3940285 | 0.97 | TDP1 (0.55) | TDP1EYA2APPACEBLM | |
| SCHEMBL233033 | 0.97 | TDP1 (0.55) | TDP1EYA2APPACEBLM | |
| SCHEMBL12798538 | 0.86 | TDP1 (0.74) | TDP1EYA2APPACEBLM | |
| SCHEMBL20906342 | 0.86 | TDP1 (0.74) | TDP1EYA2APPACEBLM | |
| SCHEMBL9157962 | 0.86 | TDP1 (0.74) | TDP1EYA2APPACEBLM | |
| Nitrilotriacetic Acid SCHEMBL27683262 | 0.85 | TDP1 (0.61) | TDP1EYA2APPACEBLM | |
| Nitrilotriacetic Acid SCHEMBL157958 | 0.85 | TDP1 (0.69) | TDP1EYA2APPACEBLM | |
| SCHEMBL3749558 | 0.85 | TDP1 (0.41) | TDP1EYA2APPACEBLM | |
| Nitrilotriacetic Acid SCHEMBL9064058 | 0.85 | TDP1 (0.69) | TDP1EYA2APPACEBLM | |
| Nitrilotriacetic Acid SCHEMBL156670 | 0.85 | TDP1 (0.69) | TDP1EYA2APPACEBLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2473480-B1 | NOVEL ANTIBACTERIAL HYDROXYPHENYL COMPOUND | FAB PHARMA SAS (FR) | 2016-06-01 | — | — | EP | disclosed |
| US-9321769-B2 | Heterocyclic acrylamides and their use as pharmaceuticals | FAB PHARMA S.A.S. (FR) | 2016-04-26 | — | — | US | disclosed |
| US-9272985-B2 | Antibacterial hydroxyphenyl compound | FAB PHARMA S.A.S. (FR) | 2016-03-01 | — | — | US | disclosed |
| US-20150232466-A1 | NOVEL HETEROCYCLIC ACRYLAMIDES AND THEIR USE AS PHARMACEUTICALS | FAB PHARMA S.A.S. (FR) | 2015-08-20 | — | — | US | disclosed |
| US-9051321-B2 | Heterocyclic acrylamides and their use as pharmaceuticals | FAB PHARMA S.A.S. (FR) | 2015-06-09 | — | — | US | disclosed |
| US-20140357617-A1 | NOVEL HETEROCYCLIC ACRYLAMIDES AND THEIR USE AS PHARMACEUTICALS | FAB PHARMA S.A.S. (FR) | 2014-12-04 | — | — | US | disclosed |
| US-8846711-B2 | Heterocyclic acrylamides and their use as pharmaceuticals | FAB PHARMA S.A.S. (FR) | 2014-09-30 | — | — | US | disclosed |
| EP-2501693-B1 | AZA HETEROCYCLIC ACRYLAMIDES AND THEIR USE AS BACTERICIDES | FAB PHARMA SAS (FR) | 2014-09-17 | — | — | EP | disclosed |
| EP-2491021-B1 | NOVEL ACYLPIPERAZINONES AND THEIR USE AS PHARMACEUTICALS | FAB PHARMA SAS (FR) | 2014-04-23 | — | — | EP | disclosed |
| US-8623865-B2 | Acylpiperazinones and their use as pharmaceuticals | FAB PHARMA S.A.S. (FR) | 2014-01-07 | — | — | US | disclosed |
| EP-2501693-A1 | NOVEL HETEROCYCLIC ACRYLAMIDES AND THEIR USE AS PHARMACEUTICALS | FAB Pharma SAS (FR) | 2012-09-26 | — | — | EP | disclosed |
| US-20120232155-A1 | NOVEL ANTIBACTERIAL HYDROXYPHENYL COMPOUND | FAB PHARMA S.A.S. (FR) | 2012-09-13 | — | — | US | disclosed |
| US-20120232079-A1 | NOVEL ACYLPIPERAZINONES AND THEIR USE AS PHARMACEUTICALS | FAB PHARMA S.A.S. (FR) | 2012-09-13 | — | — | US | disclosed |
| EP-2491021-A1 | NOVEL ACYLPIPERAZINONES AND THEIR USE AS PHARMACEUTICALS | FAB Pharma SAS (FR) | 2012-08-29 | — | — | EP | disclosed |
| EP-2473480-A1 | NOVEL ANTIBACTERIAL HYDROXYPHENYL COMPOUND | FAB Pharma SAS (FR) | 2012-07-11 | — | — | EP | disclosed |
| US-20120148517-A1 | Hair Relaxing and Straightening Compositions | INTERNATIONAL FLORA TECHNOLOGIES, LTD. (US) | 2012-06-14 | — | — | US | disclosed |
| WO-2012078658-A1 | HAIR RELAXING AND STRAIGHTENING COMPOSITIONS | INTERNATIONAL FLORA TECHNOLOGIES, LTD. (US) | 2012-06-14 | — | — | WO | disclosed |
| WO-2011061214-A1 | NOVEL HETEROCYCLIC ACRYLAMIDES AND THEIR USE AS PHARMACEUTICALS | FAB PHARMA SAS (FR) | 2011-05-26 | — | — | WO | disclosed |
| WO-2011048153-A1 | NOVEL ACYLPIPERAZINONES AND THEIR USE AS PHARMACEUTICALS | FAB PHARMA SAS (FR) | 2011-04-28 | — | — | WO | disclosed |
| WO-2011026529-A1 | NOVEL ANTIBACTERIAL HYDROXYPHENYL COMPOUND | FAB PHARMA SAS (FR) | 2011-03-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120148517-A1 | Hair Relaxing and Straightening Compositions | PDE6G, SHH, DNMT3L | TDP1 649/4885EYA2 2264/4885APP 2825/4885 |
| US-20150232466-A1 | NOVEL HETEROCYCLIC ACRYLAMIDES AND THEIR USE AS PHARMACEUTICALS | ACR, AADAC, AAAS | TDP1 1066/4885EYA2 1311/4885APP 670/4885 |
| US-20120232079-A1 | NOVEL ACYLPIPERAZINONES AND THEIR USE AS PHARMACEUTICALS | AGPAT5, GNPAT, AADAC | TDP1 4744/4885EYA2 2262/4885APP 2591/4885 |
| US-20140357617-A1 | NOVEL HETEROCYCLIC ACRYLAMIDES AND THEIR USE AS PHARMACEUTICALS | ACR, AADAC, AAAS | TDP1 1066/4885EYA2 1311/4885APP 670/4885 |
| US-20120232155-A1 | NOVEL ANTIBACTERIAL HYDROXYPHENYL COMPOUND | MRPL21, VIP, DHPS | TDP1 4620/4885EYA2 2763/4885APP 2247/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.