Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | SLC6A9 | P48067 | 8/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | FDFT1 | P37268 | 2/20 | 0.36 |
| ▸ | HHAT | Q5VTY9 | 1/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.35 |
| ▸ | DRD1 | P21728 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | DRD4 | P21917 | 1/20 | 0.34 |
| ▸ | RXRA | P19793 | 1/20 | 0.34 |
| ▸ | RXRB | P28702 | 1/20 | 0.34 |
| ▸ | RXRG | P48443 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15937933 | 0.91 | KDM4E (0.46) | KDM4ENPSR1SLC6A9RXFP1FDFT1 | |
| SCHEMBL3901210 | 0.91 | KDM4E (0.46) | KDM4ENPSR1SLC6A9RXFP1FDFT1 | |
| Bromide SCHEMBL5236979 | 0.90 | KDM4E (0.46) | KDM4ENPSR1SLC6A9RXFP1FDFT1 | |
| Bromide SCHEMBL5238372 | 0.89 | KDM4E (0.45) | KDM4ENPSR1SLC6A9RXFP1FDFT1 | |
| Water SCHEMBL5230889 | 0.80 | KDM4E (0.38) | KDM4ENPSR1SLC6A9RXFP1FDFT1 | |
| SCHEMBL2916838 | 0.78 | HDAC8 (0.42) | KDM4ENPSR1DRD1ALDH1A1DRD2 | |
| Acetonitrile SCHEMBL5226956 | 0.77 | KDM4E (0.36) | KDM4ENPSR1SLC6A9RXFP1FDFT1 | |
| SCHEMBL1499097 | 0.75 | HHAT (0.48) | KDM4ENPSR1HHATDRD1 | |
| SCHEMBL4018143 | 0.75 | HHAT (0.48) | KDM4ENPSR1HHATDRD1 | |
| SCHEMBL5439863 | 0.75 | HHAT (0.48) | KDM4ENPSR1HHATDRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2011506950-A | — | — | 2011-03-03 | — | — | JP | claimed |
| US-20110041589-A1 | NEW HPCL METHOD | GENERICS [UK] LIMITED (GB) | 2011-02-24 | — | — | US | claimed |
| US-20110041589-A1 | NEW HPCL METHOD | GENERICS [UK] LIMITED (GB) | 2011-02-24 | — | — | US | disclosed |