SCHEMBL1499097

SCHEMBL1499097

O=C(O)CN1CCc2sccc2[C@H]1c1ccccc1Cl

nearest known ligand 0.60

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
HHAT Q5VTY9 4/20 0.48
LHCGR P22888 4/20 0.46
NPSR1 Q6W5P4 2/20 0.45
MAPK1 P28482 1/20 0.45
KDM4E B2RXH2 1/20 0.44
DRD1 P21728 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5439863 1.00 HHAT (0.48) HHATLHCGRNPSR1MAPK1KDM4E
SCHEMBL4018143 1.00 HHAT (0.48) HHATLHCGRNPSR1MAPK1KDM4E
Hydrochloric Acid SCHEMBL5239130 0.99 HHAT (0.47) HHATLHCGRNPSR1MAPK1KDM4E
Bromide SCHEMBL4019730 0.99 HHAT (0.47) HHATLHCGRNPSR1MAPK1KDM4E
SCHEMBL24419940 0.86 HHAT (0.52) HHATLHCGR
SCHEMBL2307868 0.86 HHAT (0.48) HHATLHCGRNPSR1MAPK1DRD1
SCHEMBL4738266 0.86 HHAT (0.48) HHATLHCGRNPSR1MAPK1DRD1
SCHEMBL2916838 0.83 HDAC8 (0.42) NPSR1KDM4EDRD1
Sulfuric Acid SCHEMBL2306919 0.82 HHAT (0.45) HHATLHCGRDRD1
SCHEMBL5769463 0.79 HHAT (0.38) HHATLHCGRNPSR1MAPK1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-2011506950-A 2011-03-03 JP claimed
US-20110041589-A1 NEW HPCL METHOD GENERICS [UK] LIMITED (GB) 2011-02-24 US claimed
EP-2220484-A2 HPLC METHOD FOR ANALYSING CLOPIDOGREL Generics [UK] Limited (GB) 2010-08-25 EP claimed
WO-2009077784-A2 HPCL METHOD FOR ANALYSING CLOPIDOGREL GENERICS [UK] LIMITED (GB) 2009-06-25 WO claimed
US-20180125782-A1 STABLE PHARMACEUTICAL COMPOSITION OF CLOPIDOGREL FREE BASE FOR ORAL AND PARENTERAL DELIVERY HUANG JINGJUN (US) 2018-05-10 US disclosed
US-9884016-B2 Stable pharmaceutical composition of clopidogrel free base for oral and parenteral delivery ASCENDIA PHARMACEUTICALS LLC 2018-02-06 US disclosed
US-20170014343-A1 STABLE PHARMACEUTICAL COMPOSITION OF CLOPIDOGREL FREE BASE FOR ORAL AND PARENTERAL DELIVERY ASCENDIA PHARMACEUTICALS LLC 2017-01-19 US disclosed
US-9480680-B2 Stable pharmaceutical composition of clopidogrel free base for oral and parenteral delivery ASCENDIA PHARMACEUTICALS LLC 2016-11-01 US disclosed
EP-2953613-A1 STABLE PHARMACEUTICAL COMPOSITION OF CLOPIDOGREL FREE BASE FOR ORAL AND PARENTERAL DELIVERY Huang, Jingjun (US) 2015-12-16 EP disclosed
WO-2014124132-A1 STABLE PHARMACEUTICAL COMPOSITION OF CLOPIDOGREL FREE BASE FOR ORAL AND PARENTERAL DELIVERY HUANG JINGJUN (US) 2014-08-14 WO disclosed
US-20140227360-A1 STABLE PHARMACEUTICAL COMPOSITION OF CLOPIDOGREL FREE BASE FOR ORAL AND PARENTERAL DELIVERY ASCENDIA PHARMACEUTICALS LLC 2014-08-14 US disclosed
WO-2013133620-A1 PHARMACEUTICAL COMPOSITION COMPRISING CLOPIDOGREL AND ASPIRIN AND PROCESS FOR PREPARING THE SAME YUHAN CORPORATION (KR) 2013-09-12 WO disclosed
EP-2121704-A2 POLYMORPHIC FORMS OF CLOPIDOGREL HYDROBROMIDE KRKA, tovarna zdravil, d.d., Novo mesto (SI) 2009-11-25 EP disclosed
WO-2008108742-A2 POLYMORPHIC FORMS OF CLOPIDOGREL HYDROBROMIDE KRKA, TOVARNA ZDRAVIL, D.D., NOVO MESTO (SI) 2008-09-12 WO disclosed
US-20070225320-A1 PROCESS FOR PREPARING CLOPIDOGREL DR. REDDY'S LABORATORIES, INC. 2007-09-27 US disclosed
EP-1750701-A1 AMORPHOUS CLOPIDOGREL HYDROCHLORIDE AND ITS ANTITHROMBOTIC USE IVAX Pharmaceuticals s.r.o. (CZ) 2007-02-14 EP disclosed
EP-1750701-A1 AMORPHOUS CLOPIDOGREL HYDROCHLORIDE AND ITS ANTITHROMBOTIC USE IVAX Pharmaceuticals s.r.o. (CZ) 2007-02-14 EP disclosed
WO-2006023676-A1 CLOPIDOGREL NAPSYLATE SALT IVAX PHARMACEUTICALS S.R.O. (CZ) 2006-03-02 WO disclosed
WO-2005117866-A1 AMORPHOUS CLOPIDOGREL HYDROCHLORIDE AND ITS ANTITHROMBOTIC USE IVAX PHARMACEUTICALS S.R.O. (CZ) 2005-12-15 WO disclosed
WO-2005117866-A1 AMORPHOUS CLOPIDOGREL HYDROCHLORIDE AND ITS ANTITHROMBOTIC USE IVAX PHARMACEUTICALS S.R.O. (CZ) 2005-12-15 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140227360-A1 STABLE PHARMACEUTICAL COMPOSITION OF CLOPIDOGREL FREE BASE FOR ORAL AND PARENTERAL DELIVERY CEL, SELP, P2RY12 HHAT 1687/4885LHCGR 3886/4885NPSR1 569/4885
US-20180125782-A1 STABLE PHARMACEUTICAL COMPOSITION OF CLOPIDOGREL FREE BASE FOR ORAL AND PARENTERAL DELIVERY P2RY12, P2RY11, SELP HHAT 1317/4885LHCGR 3774/4885NPSR1 310/4885
US-20070225320-A1 PROCESS FOR PREPARING CLOPIDOGREL PFKP, SELP, P2RY13 HHAT 3793/4885LHCGR 3799/4885NPSR1 626/4885
US-20170014343-A1 STABLE PHARMACEUTICAL COMPOSITION OF CLOPIDOGREL FREE BASE FOR ORAL AND PARENTERAL DELIVERY P2RY12, P2RY11, SELP HHAT 1317/4885LHCGR 3774/4885NPSR1 310/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.