Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Voglibose. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM known ✓ | O43451 | 18/20 | 1.00 |
| ▸ | GAA known ✓ | P10253 | 2/20 | 1.00 |
| ▸ | SI known ✓ | P14410 | 17/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Voglibose SCHEMBL2906102 | 1.00 | MGAM (1.00) | MGAMGAALMNASI | |
| Voglibose SCHEMBL27565869 | 1.00 | MGAM (1.00) | MGAMGAALMNASI | |
| Voglibose SCHEMBL5882 | 1.00 | MGAM (1.00) | MGAMGAALMNASI | |
| Voglibose SCHEMBL17396338 | 1.00 | MGAM (1.00) | MGAMGAALMNASI | |
| Voglibose SCHEMBL6245153 | 0.98 | MGAM (0.97) | MGAMGAALMNASI | |
| Voglibose SCHEMBL5028621 | 0.98 | MGAM (0.97) | MGAMGAALMNASI | |
| Voglibose SCHEMBL11286105 | 0.98 | MGAM (0.97) | MGAMGAALMNASI | |
| Voglibose SCHEMBL3244186 | 0.98 | MGAM (0.97) | MGAMGAALMNASI | |
| Voglibose SCHEMBL10670275 | 0.98 | MGAM (0.97) | MGAMGAALMNASI | |
| Voglibose SCHEMBL1116195 | 0.98 | MGAM (0.97) | MGAMGAALMNASI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2048134-B1 | MEPTAZINOL BILIGAND DERIVATIVES AND/OR THEIR SALTS, PREPARATION METHOD AND USES THEREOF | UNIV FUDAN (CN) | 2015-09-23 | — | — | EP | claimed |
| EP-3675838-A1 | LYMPHATIC SYSTEM-DIRECTING LIPID PRODRUGS | Puretecch LYT, Inc. (US) | 2020-07-08 | — | — | EP | disclosed |
| WO-2019046491-A1 | LYMPHATIC SYSTEM-DIRECTING LIPID PRODRUGS | ARIYA THERAPEUTICS, INC. (US) | 2019-03-07 | — | — | WO | disclosed |
| CN-103868867-A | Screening model and screening method for alpha-glucosidase inhibitor, and application of screening method | UNIV SICHUAN NORMAL | 2014-06-18 | — | — | CN | disclosed |
| WO-2013081563-A2 | STABLE TABLET FORMULATIONS | BILGIC MAHMUT (TR) | 2013-06-06 | — | — | WO | disclosed |