Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Voglibose. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM known ✓ | O43451 | 18/20 | 0.97 |
| ▸ | GAA known ✓ | P10253 | 2/20 | 0.97 |
| ▸ | SI known ✓ | P14410 | 17/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.97 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Voglibose SCHEMBL17396338 | 0.98 | MGAM (1.00) | MGAMGAALMNASI | |
| Voglibose SCHEMBL5882 | 0.98 | MGAM (1.00) | MGAMGAALMNASI | |
| Voglibose SCHEMBL27565869 | 0.98 | MGAM (1.00) | MGAMGAALMNASI | |
| Voglibose SCHEMBL14992258 | 0.98 | MGAM (1.00) | MGAMGAALMNASI | |
| Voglibose SCHEMBL2906102 | 0.98 | MGAM (1.00) | MGAMGAALMNASI | |
| Voglibose SCHEMBL5028621 | 0.97 | MGAM (0.97) | MGAMGAALMNASI | |
| Voglibose SCHEMBL1116195 | 0.97 | MGAM (0.97) | MGAMGAALMNASI | |
| Voglibose SCHEMBL3244186 | 0.97 | MGAM (0.97) | MGAMGAALMNASI | |
| Voglibose SCHEMBL10670275 | 0.97 | MGAM (0.97) | MGAMGAALMNASI | |
| Voglibose SCHEMBL11286105 | 0.97 | MGAM (0.97) | MGAMGAALMNASI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115703710-A | Improved preparation method of voglibose | 吉林天衡药业有限公司 | 2023-02-17 | — | — | CN | claimed |
| EP-3236933-B1 | A NASAL COMPOSITION CONTAINING SEA WATER AS STABILITY-IMPROVING EXCIPIENT | JADRAN GALENSKI LABORATORIJ D D (HR) | 2018-11-14 | — | — | EP | claimed |
| CN-101279925-B | Tetrabenzyl voglibose, preparation and application thereof | YUN LEI | 2011-10-19 | — | — | CN | claimed |
| WO-2005030698-A1 | PROCESS FOR THE PREPARATION OF VOGLIBOSE | RANBAXY LABORATORIES LIMITED (IN) | 2005-04-07 | — | — | WO | claimed |
| CN-115703710-A | Improved preparation method of voglibose | 吉林天衡药业有限公司 | 2023-02-17 | — | — | CN | disclosed |
| CN-115703710-A | Improved preparation method of voglibose | 吉林天衡药业有限公司 | 2023-02-17 | — | — | CN | disclosed |
| CN-101279925-B | Tetrabenzyl voglibose, preparation and application thereof | YUN LEI | 2011-10-19 | — | — | CN | disclosed |
| CN-101279925-A | Tetrabenzyl voglibose, preparation and application thereof | YUN LEI (CN) | 2008-10-08 | — | — | CN | disclosed |
| CN-1882526-A | Process for the preparation of voglibose | RANBAXY LAB LTD (IN) | 2006-12-20 | — | — | CN | disclosed |
| CN-1882526-A | Process for the preparation of voglibose | RANBAXY LAB LTD (IN) | 2006-12-20 | — | — | CN | disclosed |
| WO-2005030698-A1 | PROCESS FOR THE PREPARATION OF VOGLIBOSE | RANBAXY LABORATORIES LIMITED (IN) | 2005-04-07 | — | — | WO | disclosed |
| WO-2005030698-A1 | PROCESS FOR THE PREPARATION OF VOGLIBOSE | RANBAXY LABORATORIES LIMITED (IN) | 2005-04-07 | — | — | WO | disclosed |
| EP-0258727-A1 | Process for the preparation of an o-naphthoquinone diazide sulfonic-acid ester | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-03-09 | — | — | EP | disclosed |