Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Voglibose. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM known ✓ | O43451 | 18/20 | 0.97 |
| ▸ | GAA known ✓ | P10253 | 2/20 | 0.97 |
| ▸ | SI known ✓ | P14410 | 17/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.97 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Voglibose SCHEMBL17396338 | 0.98 | MGAM (1.00) | MGAMGAALMNASI | |
| Voglibose SCHEMBL5882 | 0.98 | MGAM (1.00) | MGAMGAALMNASI | |
| Voglibose SCHEMBL27565869 | 0.98 | MGAM (1.00) | MGAMGAALMNASI | |
| Voglibose SCHEMBL2906102 | 0.98 | MGAM (1.00) | MGAMGAALMNASI | |
| Voglibose SCHEMBL14992258 | 0.98 | MGAM (1.00) | MGAMGAALMNASI | |
| Voglibose SCHEMBL6245153 | 0.97 | MGAM (0.97) | MGAMGAALMNASI | |
| Voglibose SCHEMBL5028621 | 0.97 | MGAM (0.97) | MGAMGAALMNASI | |
| Voglibose SCHEMBL10670275 | 0.97 | MGAM (0.97) | MGAMGAALMNASI | |
| Voglibose SCHEMBL11286105 | 0.97 | MGAM (0.97) | MGAMGAALMNASI | |
| Voglibose SCHEMBL1116195 | 0.97 | MGAM (0.97) | MGAMGAALMNASI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1991510-A2 | ADDITIVE BUILDING MATERIAL MIXTURES COMPRISING SWELLABLE POLYMER STRUCTURES | Evonik Röhm GmbH (DE) | 2008-11-19 | — | — | EP | claimed |
| EP-1236709-B1 | A process for the preparation of terbinafine | DIPHARMA FRANCIS SRL (IT) | 2007-12-05 | — | — | EP | claimed |
| WO-2007099006-A2 | ADDITIVE BUILDING MATERIAL MIXTURES COMPRISING SWELLABLE POLYMER STRUCTURES | EVONIK RÖHM GMBH (DE) | 2007-09-07 | — | — | WO | claimed |
| EP-0866086-B1 | Process for the preparation of SiOH-funktional carbosilane dendrimers | BAYER AG (DE) | 2003-07-23 | — | — | EP | claimed |
| EP-1156864-B1 | CO-CRYSTALLIZATION PROCESS | REUTER CHEMISCHE APPBAU KG (DE) | 2003-05-14 | — | — | EP | claimed |
| EP-0866086-A2 | Process for the preparation of SiOH-funktional carbosilane dendrimers | BAYER AG (DE) | 1998-09-23 | — | — | EP | claimed |
| EP-0272667-A2 | Method for the preparation of the demalonyl bond of lactonic macrolides | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-06-29 | — | — | EP | claimed |
| EP-1841471-B1 | ANTIMICROBIAL MEDICAL PRODUCT, METHOD FOR THE PRODUCTION THEREOF AND USE THEREOF | AESCULAP AG (DE) | 2010-07-28 | — | — | EP | disclosed |
| EP-1841471-A2 | ANTIMICROBIAL MEDICAL PRODUCT, METHOD FOR THE PRODUCTION THEREOF AND USE THEREOF | Aesculap AG & Co. KG (DE) | 2007-10-10 | — | — | EP | disclosed |
| WO-2007028607-A2 | ANTIMICROBIAL MEDICAL PRODUCT, METHOD FOR THE PRODUCTION THEREOF AND USE THEREOF | AESCULAP AG & CO. KG (DE) | 2007-03-15 | — | — | WO | disclosed |
| EP-1475377-B1 | Derivatives of indole and their use as phosphodiesterase 4 inhibitors | ELBION AG (DE) | 2006-06-21 | — | — | EP | disclosed |
| EP-1615912-A1 | 4-, 6- O 7-HYDROXYINDOLES HAVING N-OXIDE GROUPS AND THE USE THEREOF AS THERAPEUTIC AGENTS | Elbion AG (DE) | 2006-01-18 | — | — | EP | disclosed |
| EP-1615911-A1 | 5-HYDROXYINDOLES WITH N-OXIDE GROUPS AND USE THEREOF AS A PHOSPHODIESTERASE 4 INHIBITOR | Elbion AG (DE) | 2006-01-18 | — | — | EP | disclosed |
| WO-1990000189-A1 | WASHING AGENT ADDITIVES WITH IMPROVED DISPERSIBILITY | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 1990-01-11 | — | — | WO | disclosed |
| EP-0318649-A2 | Positive-working radiation-sensitive composistion and radiation-sensitive recording material produced therefrom for high-energy radiation | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-06-07 | — | — | EP | disclosed |
| EP-0262344-A2 | N-alkylated quaternary nitrogen-containing heterocycles, process for their preparation and their use in pharmaceutical compositions | MEDICEChem.-Pharm. Fabrik Pütter GmbH & Co. KG (DE) | 1988-04-06 | — | — | EP | disclosed |
| EP-0260428-A2 | Cationic surfactants and pharmaceutical compositions containing them | MEDICEChem.-Pharm. Fabrik Pütter GmbH & Co. KG (DE) | 1988-03-23 | — | — | EP | disclosed |
| EP-0257400-A2 | Pharmaceutical compositions containing cationic surfactants | MEDICEChem.-Pharm. Fabrik Pütter GmbH & Co. KG (DE) | 1988-03-02 | — | — | EP | disclosed |
| EP-0223063-A2 | Process for the continuous preparation of cross-linked gelatinous polymers with a small particle size | BASF Aktiengesellschaft (DE) | 1987-05-27 | — | — | EP | disclosed |
| EP-0187315-A2 | Basic quinolonecarboxylic-acid preparations | BAYER AG (DE) | 1986-07-16 | — | — | EP | disclosed |