Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 14/20 | 0.59 |
| ▸ | PTGS2 | P35354 | 14/20 | 0.59 |
| ▸ | ALOX5 | P09917 | 12/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.59 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.59 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.59 |
| ▸ | TTR | P02766 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14992948 | 1.00 | PTGS1 (0.59) | PTGS1PTGS2ALOX5CYP2C9CYP1A2 | |
| SCHEMBL1824102 | 0.87 | PTGS1 (0.74) | PTGS1PTGS2ALOX5CYP2C9CYP1A2 | |
| SCHEMBL1824103 | 0.87 | PTGS1 (0.74) | PTGS1PTGS2ALOX5CYP2C9CYP1A2 | |
| SCHEMBL23829549 | 0.82 | PTGS1 (0.57) | PTGS1PTGS2ALOX5CYP2C9CYP1A2 | |
| SCHEMBL29876789 | 0.82 | PTGS1 (0.57) | PTGS1PTGS2ALOX5CYP2C9CYP1A2 | |
| SCHEMBL13271785 | 0.79 | TUBB1 (0.47) | PTGS1PTGS2ALOX5CYP2C9CYP1A2 | |
| SCHEMBL10551448 | 0.79 | CA1 (0.52) | PTGS1PTGS2ALOX5CYP2C9CYP1A2 | |
| SCHEMBL2091258 | 0.78 | PTGS1 (0.57) | PTGS1PTGS2ALOX5CYP2C9CYP1A2 | |
| SCHEMBL21758872 | 0.78 | PTGS1 (0.63) | PTGS1PTGS2ALOX5CYP2C9CYP1A2 | |
| SCHEMBL13357357 | 0.78 | ALOX5 (0.59) | PTGS1PTGS2ALOX5CYP2C9CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9163102-B2 | Soluble branched polymers | ISP INVESTMENTS INC. (US) | 2015-10-20 | — | — | US | disclosed |
| US-20140303313-A1 | SOLUBLE BRANCHED POLYMERS | ISP INVESTMENTS INC. (US) | 2014-10-09 | — | — | US | disclosed |
| WO-2013082359-A1 | SOLUBLE BRANCHED POLYMERS | ISP INVESTMENTS INC. (US) | 2013-06-06 | — | — | WO | disclosed |