Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 15/20 | 0.63 |
| ▸ | PTGS2 | P35354 | 15/20 | 0.63 |
| ▸ | ALOX5 | P09917 | 12/20 | 0.63 |
| ▸ | TTR | P02766 | 1/20 | 0.63 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.57 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1824102 | 0.85 | PTGS1 (0.74) | PTGS1PTGS2ALOX5TTRCYP1A2 | |
| SCHEMBL1824103 | 0.85 | PTGS1 (0.74) | PTGS1PTGS2ALOX5TTRCYP1A2 | |
| SCHEMBL14992948 | 0.78 | PTGS1 (0.59) | PTGS1PTGS2ALOX5TTRCYP1A2 | |
| SCHEMBL14992949 | 0.78 | PTGS1 (0.59) | PTGS1PTGS2ALOX5TTRCYP1A2 | |
| SCHEMBL10946633 | 0.77 | PTGS1 (1.00) | PTGS1PTGS2ALOX5TTR | |
| SCHEMBL12644239 | 0.77 | PTGS1 (1.00) | PTGS1PTGS2ALOX5TTR | |
| SCHEMBL2091258 | 0.76 | PTGS1 (0.57) | PTGS1PTGS2ALOX5TTRCYP1A2 | |
| SCHEMBL2091256 | 0.76 | PTGS1 (0.57) | PTGS1PTGS2ALOX5TTRCYP1A2 | |
| SCHEMBL13357357 | 0.76 | ALOX5 (0.59) | PTGS1PTGS2ALOX5TTRCYP1A2 | |
| SCHEMBL38650753 | 0.74 | ALDH1A1 (0.38) | PTGS1PTGS2ALOX5TTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020039297-A1 | NOVEL COMPOUNDS AND THEIR USE IN PREPARATION OF ELAFIBRANOR AND PHARMACEUTICAL ACCEPTABLE SALTS THEREOF | MANKIND PHARMA LTD. (IN) | 2020-02-27 | — | — | WO | disclosed |