Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2L1 | Q07817 | 3/20 | 0.47 |
| ▸ | BCL2 | P10415 | 1/20 | 0.47 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.47 |
| ▸ | BCL2A1 | Q16548 | 1/20 | 0.47 |
| ▸ | TYR | P14679 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 5/20 | 0.38 |
| ▸ | LDHA | P00338 | 3/20 | 0.37 |
| ▸ | LDHB | P07195 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14995997 | 0.92 | BCL2L1 (0.50) | BCL2L1BCL2MCL1BCL2A1ALOX5 | |
| SCHEMBL14995995 | 0.91 | BCL2L1 (0.43) | BCL2L1BCL2MCL1BCL2A1TYR | |
| SCHEMBL14995987 | 0.87 | BCL2L1 (0.51) | BCL2L1BCL2MCL1BCL2A1HPGD | |
| SCHEMBL14995986 | 0.84 | BCL2L1 (0.46) | BCL2L1BCL2MCL1BCL2A1ALOX5 | |
| SCHEMBL14995985 | 0.83 | TYR (0.41) | BCL2L1BCL2MCL1BCL2A1TYR | |
| SCHEMBL14995970 | 0.81 | BCL2L1 (0.64) | BCL2L1BCL2MCL1BCL2A1HTT | |
| SCHEMBL14995965 | 0.79 | BCL2L1 (0.66) | BCL2L1BCL2MCL1BCL2A1LDHA | |
| SCHEMBL14995966 | 0.76 | BCL2L1 (0.42) | BCL2L1BCL2MCL1BCL2A1TYR | |
| SCHEMBL14995968 | 0.75 | BCL2L1 (0.43) | BCL2L1BCL2MCL1BCL2A1TYR | |
| SCHEMBL5920126 | 0.75 | HTT (0.48) | TYRHTTNPC1HPGDMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8455540-B2 | Gossypol and apogossypol derivatives, preparation thereof and uses thereof | UNIVERSITE DU MAINE (LE MANS) (FR) | 2013-06-04 | — | — | US | disclosed |