Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 8/20 | 0.54 |
| ▸ | DRD2 | P14416 | 1/20 | 0.52 |
| ▸ | DRD1 | P21728 | 1/20 | 0.52 |
| ▸ | HTR2A | P28223 | 1/20 | 0.52 |
| ▸ | HTR2C | P28335 | 1/20 | 0.52 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.52 |
| ▸ | HTR6 | P50406 | 1/20 | 0.52 |
| ▸ | NQO2 | P16083 | 2/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | PGR | P06401 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | IDO1 | P14902 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2201343 | 0.90 | HTR7 (0.59) | HTR7DRD2DRD1HTR2AHTR2C | |
| SCHEMBL18854022 | 0.87 | PGR (0.56) | HTR7DRD2DRD1HTR2AHTR2C | |
| SCHEMBL2988221 | 0.87 | PGR (0.56) | HTR7DRD2DRD1HTR2AHTR2C | |
| SCHEMBL9651965 | 0.84 | HTR7 (0.54) | HTR7DRD2DRD1HTR2AHTR2C | |
| SCHEMBL12225622 | 0.84 | HTR7 (0.51) | HTR7DRD2DRD1HTR2AHTR2C | |
| SCHEMBL1543064 | 0.82 | HTR7 (0.51) | HTR7DRD2DRD1HTR2AHTR2C | |
| SCHEMBL1455904 | 0.81 | HTR7 (0.60) | HTR7DRD2DRD1HTR2AHTR2C | |
| SCHEMBL10264450 | 0.80 | HDAC1 (0.56) | HTR7DRD2DRD1HTR2AHTR2C | |
| SCHEMBL8138050 | 0.77 | HTR7 (0.48) | HTR7DRD2DRD1HTR2AHTR2C | |
| SCHEMBL7041168 | 0.77 | IDO1 (0.70) | HTR7DRD2MAPTIDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8455535-B2 | Heteroaryl dihydroindolones as kinase inhibitors | ALLERGAN, INC. (US) | 2013-06-04 | — | — | US | disclosed |