SCHEMBL1499653

SCHEMBL1499653

CC(C)C(=O)NCCCO

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGS1 P23219 1/20 0.55
KCNH2 Q12809 1/20 0.55
KMT2A Q03164 3/20 0.52
CYP2C19 P33261 2/20 0.52
CYP2D6 P10635 1/20 0.52
CYP2C9 P11712 1/20 0.52
ALDH1A1 P00352 2/20 0.44
USP2 O75604 2/20 0.44
MEN1 O00255 2/20 0.44
MAPT P10636 1/20 0.44
ALDH1A2 O94788 1/20 0.43
ALDH2 P05091 1/20 0.43
ALDH1A3 P47895 1/20 0.43
TSHR P16473 2/20 0.39
DPP7 Q9UHL4 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
CA1 P00915 2/20 0.38
CA2 P00918 2/20 0.38
CA12 O43570 1/20 0.38
CA9 Q16790 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7349570 0.93 KMT2A (0.50) PTGS1KCNH2KMT2ACYP2C19CYP2D6
SCHEMBL27053773 0.91 ALDH1A1 (0.50) PTGS1KCNH2KMT2ACYP2C19CYP2D6
SCHEMBL861034 0.87 KMT2A (0.57) PTGS1KCNH2KMT2ACYP2C19CYP2D6
SCHEMBL22917014 0.87 KMT2A (0.57) PTGS1KCNH2KMT2ACYP2C19CYP2D6
SCHEMBL12884399 0.86 PTGS1 (0.52) PTGS1KCNH2KMT2ACYP2C19CYP2D6
SCHEMBL146290 0.85
SCHEMBL23839910 0.85 ALDH1A1 (0.58) KMT2ACYP2C19CYP2D6CYP2C9ALDH1A1
SCHEMBL23188735 0.85 ALDH1A1 (0.58) KMT2ACYP2C19CYP2D6CYP2C9ALDH1A1
SCHEMBL17777241 0.85 ALDH1A1 (0.58) KMT2ACYP2C19CYP2D6CYP2C9ALDH1A1
SCHEMBL1399165 0.84 PTGS1 (0.58) PTGS1KCNH2KMT2ACYP2C19CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 62 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11191270-B2 Pesticide composition comprising a tetrazolyloxime derivative and a fungicide or an insecticide active substance BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2021-12-07 US claimed
US-20190104736-A1 PESTICIDE COMPOSITION COMPRISING A TETRAZOLYLOXIME DERIVATIVE AND A FUNGICIDE OR AN INSECTICIDE ACTIVE SUBSTANCE BAYER CROPSCIENCE AG (DE) 2019-04-11 US claimed
US-10188106-B2 Pesticide composition comprising a tetrazolyloxime derivative and a fungicide or an insecticide active substance BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2019-01-29 US claimed
US-20150257387-A1 PESTICIDE COMPOSITION COMPRISING A TETRAZOLYLOXIME DERIVATIVE AND A FUNGICIDE OR AN INSECTICIDE ACTIVE SUBSTANCE BAYER CROPSCIENCE AG (DE) 2015-09-17 US claimed
US-9060518-B2 Pesticide composition comprising a tetrazolyloxime derivative and a fungicide or an insecticide active substance BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2015-06-23 US claimed
JP-2011509971-A 2011-03-31 JP claimed
US-20110052555-A1 PESTICIDE COMPOSITION COMPRISING A TETRAZOLYLOXIME DERIVATIVE AND A FUNGICIDE OR AN INSECTICIDE ACTIVE SUBSTANCE BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2011-03-03 US claimed
EP-2234489-A2 PESTICIDE COMPOSITION COMPRISING A TETRAZOLYLOXIME DERIVATIVE AND A FUNGICIDE OR AN INSECTICIDE ACTIVE SUBSTANCE Bayer CropScience AG (DE) 2010-10-06 EP claimed
WO-2009090181-A2 PESTICIDE COMPOSITION COMPRISING A TETRAZOLYLOXIME DERIVATIVE AND A FUNGICIDE OR AN INSECTICIDE ACTIVE SUBSTANCE BAYER CROPSCIENCE SA (FR) 2009-07-23 WO claimed
US-12036209-B2 Compounds and methods for the targeted degradation of Interleukin-1 receptor-associated kinase 4 polypeptides ARVINAS OPERATIONS, INC. (US) 2024-07-16 US disclosed
US-10188106-B2 Pesticide composition comprising a tetrazolyloxime derivative and a fungicide or an insecticide active substance BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2019-01-29 US disclosed
EP-3262940-A1 PESTICIDE COMPOSITION COMPRISING A TETRAZOLYLOXIME DERIVATIVE AND AN INSECTICIDE ACTIVE SUBSTANCE Bayer Intellectual Property GmbH (DE) 2018-01-03 EP disclosed
US-20170355705-A1 SUBSTITUTED BRIDGED UREA ANALOGS AS SIRTUIN MODULATORS GLAXOSMITHKLINE INTELLECTUAL PROPERTY (NO.2) LIMITED (GB) 2017-12-14 US disclosed
US-9663488-B2 Metalloenzyme inhibitor compounds VIAMET PHARMACEUTICALS, INC. (US) 2017-05-30 US disclosed
CN-1805923-A Benzamide derivative or salt thereof ASTELLAS PHARMA INC (JP) 2006-07-19 CN disclosed
EP-1632477-A1 BENZAMIDE DERIVATIVE OR SALT THEREOF Astellas Pharma Inc. (JP) 2006-03-08 EP disclosed
US-20050070439-A1 Tetrazoyl oxime derivative and agricultural chemical containing the same as active ingredient DAINIPPON INK AND CHEMICALS, INC. (JP) 2005-03-31 US disclosed
EP-1426371-A1 TETRAZOYL OXIME DERIVATIVE AND AGRICULTURAL CHEMICAL CONTAINING THE SAME AS ACTIVE INGREDIENT DAINIPPON INK AND CHEMICALS, INC. (JP) 2004-06-09 EP disclosed
US-5659065-A CHEMICAL INTERMEDIATES FOR MEDICINAL ACTIVE AGENTS NOVARTIS CORPORATION (US) 1997-08-19 US disclosed
EP-0678500-A1 Alpha-amino alkanoic acids and reduction products as intermediates in the preparation of renin inhibitors CIBA-GEIGY AG (CH) 1995-10-25 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11191270-B2 Pesticide composition comprising a tetrazolyloxime derivative and a fungicide or an insecticide active substance DDT, TH, PRDX5 PTGS1 3943/4885KCNH2 1938/4885KMT2A 839/4885
US-12036209-B2 Compounds and methods for the targeted degradation of Interleukin-1 receptor-associated kinase 4 polypeptides IRAK1, IRAK4, IRAK2 PTGS1 2780/4885KCNH2 4850/4885KMT2A 2172/4885
US-20170355705-A1 SUBSTITUTED BRIDGED UREA ANALOGS AS SIRTUIN MODULATORS SIRT1, SIRT3, SIRT2 PTGS1 736/4885KCNH2 4064/4885KMT2A 1922/4885
US-20110052555-A1 PESTICIDE COMPOSITION COMPRISING A TETRAZOLYLOXIME DERIVATIVE AND A FUNGICIDE OR AN INSECTICIDE ACTIVE SUBSTANCE DDT, TH, PRDX5 PTGS1 3943/4885KCNH2 1938/4885KMT2A 839/4885
US-20150257387-A1 PESTICIDE COMPOSITION COMPRISING A TETRAZOLYLOXIME DERIVATIVE AND A FUNGICIDE OR AN INSECTICIDE ACTIVE SUBSTANCE DDT, TH, PRDX5 PTGS1 3943/4885KCNH2 1938/4885KMT2A 839/4885
US-20050070439-A1 Tetrazoyl oxime derivative and agricultural chemical containing the same as active ingredient TH, CYP2E1, PAOX PTGS1 90/4885KCNH2 2291/4885KMT2A 1419/4885
US-20190104736-A1 PESTICIDE COMPOSITION COMPRISING A TETRAZOLYLOXIME DERIVATIVE AND A FUNGICIDE OR AN INSECTICIDE ACTIVE SUBSTANCE DDT, TH, PRDX5 PTGS1 3943/4885KCNH2 1938/4885KMT2A 839/4885
US-10188106-B2 Pesticide composition comprising a tetrazolyloxime derivative and a fungicide or an insecticide active substance DDT, TH, PRDX5 PTGS1 3943/4885KCNH2 1938/4885KMT2A 839/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.