SCHEMBL1499772

SCHEMBL1499772

CCCC(=O)NCCC[O]

nearest known ligand 0.69

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
CASP2 P42575 1/20 0.69
NAAA Q02083 1/20 0.53
FAAH O00519 3/20 0.50
MEN1 O00255 1/20 0.50
KMT2A Q03164 1/20 0.50
DNM1 Q05193 1/20 0.47
HDAC3 O15379 1/20 0.46
HDAC1 Q13547 1/20 0.46
HDAC2 Q92769 1/20 0.46
HDAC8 Q9BY41 1/20 0.46
HDAC6 Q9UBN7 1/20 0.46
TSHR P16473 1/20 0.45
CNR1 P21554 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4684597 0.93 CASP2 (0.73) CASP2NAAAFAAHMEN1KMT2A
SCHEMBL7537764 0.88 CASP2 (0.86) CASP2NAAAFAAHMEN1KMT2A
SCHEMBL14576993 0.88 CASP2 (0.78) CASP2NAAAFAAHMEN1KMT2A
SCHEMBL14199967 0.86 CASP2 (0.91) CASP2NAAAFAAHMEN1KMT2A
SCHEMBL605189 0.86
SCHEMBL1553172 0.86 CASP2 (0.83) CASP2NAAAFAAHMEN1KMT2A
SCHEMBL3261255 0.85 FAAH (0.70) CASP2NAAAFAAHDNM1
SCHEMBL1051838 0.84 CASP2 (0.61) CASP2NAAAFAAHMEN1KMT2A
Water SCHEMBL28379853 0.84 CASP2 (0.79) CASP2NAAAFAAHMEN1KMT2A
SCHEMBL28209446 0.84 CASP2 (0.79) CASP2NAAAFAAHMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11191270-B2 Pesticide composition comprising a tetrazolyloxime derivative and a fungicide or an insecticide active substance BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2021-12-07 US claimed
US-20190104736-A1 PESTICIDE COMPOSITION COMPRISING A TETRAZOLYLOXIME DERIVATIVE AND A FUNGICIDE OR AN INSECTICIDE ACTIVE SUBSTANCE BAYER CROPSCIENCE AG (DE) 2019-04-11 US claimed
US-10188106-B2 Pesticide composition comprising a tetrazolyloxime derivative and a fungicide or an insecticide active substance BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2019-01-29 US claimed
US-20150257387-A1 PESTICIDE COMPOSITION COMPRISING A TETRAZOLYLOXIME DERIVATIVE AND A FUNGICIDE OR AN INSECTICIDE ACTIVE SUBSTANCE BAYER CROPSCIENCE AG (DE) 2015-09-17 US claimed
US-9060518-B2 Pesticide composition comprising a tetrazolyloxime derivative and a fungicide or an insecticide active substance BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2015-06-23 US claimed
JP-2011509971-A 2011-03-31 JP claimed
US-20110052555-A1 PESTICIDE COMPOSITION COMPRISING A TETRAZOLYLOXIME DERIVATIVE AND A FUNGICIDE OR AN INSECTICIDE ACTIVE SUBSTANCE BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2011-03-03 US claimed
EP-2234489-A2 PESTICIDE COMPOSITION COMPRISING A TETRAZOLYLOXIME DERIVATIVE AND A FUNGICIDE OR AN INSECTICIDE ACTIVE SUBSTANCE Bayer CropScience AG (DE) 2010-10-06 EP claimed
WO-2009090181-A2 PESTICIDE COMPOSITION COMPRISING A TETRAZOLYLOXIME DERIVATIVE AND A FUNGICIDE OR AN INSECTICIDE ACTIVE SUBSTANCE BAYER CROPSCIENCE SA (FR) 2009-07-23 WO claimed
EP-0686035-B1 AGENT FOR PROPHYLAXIS OR TREATMENT OF CATARACT OTSUKA PHARMA CO LTD (JP) 2000-04-26 EP claimed
US-11191270-B2 Pesticide composition comprising a tetrazolyloxime derivative and a fungicide or an insecticide active substance BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2021-12-07 US disclosed
US-20190104736-A1 PESTICIDE COMPOSITION COMPRISING A TETRAZOLYLOXIME DERIVATIVE AND A FUNGICIDE OR AN INSECTICIDE ACTIVE SUBSTANCE BAYER CROPSCIENCE AG (DE) 2019-04-11 US disclosed
US-10188106-B2 Pesticide composition comprising a tetrazolyloxime derivative and a fungicide or an insecticide active substance BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2019-01-29 US disclosed
EP-3262940-A1 PESTICIDE COMPOSITION COMPRISING A TETRAZOLYLOXIME DERIVATIVE AND AN INSECTICIDE ACTIVE SUBSTANCE Bayer Intellectual Property GmbH (DE) 2018-01-03 EP disclosed
US-20150257387-A1 PESTICIDE COMPOSITION COMPRISING A TETRAZOLYLOXIME DERIVATIVE AND A FUNGICIDE OR AN INSECTICIDE ACTIVE SUBSTANCE BAYER CROPSCIENCE AG (DE) 2015-09-17 US disclosed
EP-0602209-A1 OXYTOCIN ANTAGONIST OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1994-06-22 EP disclosed
EP-0382185-B1 Carbostyril derivatives OTSUKA PHARMA CO LTD (JP) 1994-06-15 EP disclosed
WO-1994001113-A1 OXYTOCIN ANTAGONIST OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) 1994-01-20 WO disclosed
US-5225402-A Vasopressin antagonist, vasodilation, hypotensive, diuretics and anticoagulants OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1993-07-06 US disclosed
EP-0382185-A2 Carbostyril derivatives OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1990-08-16 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11191270-B2 Pesticide composition comprising a tetrazolyloxime derivative and a fungicide or an insecticide active substance DDT, TH, PRDX5 CASP2 47/4885NAAA 876/4885FAAH 2130/4885
US-20110052555-A1 PESTICIDE COMPOSITION COMPRISING A TETRAZOLYLOXIME DERIVATIVE AND A FUNGICIDE OR AN INSECTICIDE ACTIVE SUBSTANCE DDT, TH, PRDX5 CASP2 47/4885NAAA 876/4885FAAH 2130/4885
US-20150257387-A1 PESTICIDE COMPOSITION COMPRISING A TETRAZOLYLOXIME DERIVATIVE AND A FUNGICIDE OR AN INSECTICIDE ACTIVE SUBSTANCE DDT, TH, PRDX5 CASP2 47/4885NAAA 876/4885FAAH 2130/4885
US-20190104736-A1 PESTICIDE COMPOSITION COMPRISING A TETRAZOLYLOXIME DERIVATIVE AND A FUNGICIDE OR AN INSECTICIDE ACTIVE SUBSTANCE DDT, TH, PRDX5 CASP2 47/4885NAAA 876/4885FAAH 2130/4885
US-10188106-B2 Pesticide composition comprising a tetrazolyloxime derivative and a fungicide or an insecticide active substance DDT, TH, PRDX5 CASP2 47/4885NAAA 876/4885FAAH 2130/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.