Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LARS1 | Q9P2J5 | 1/20 | 0.47 |
| ▸ | F2 | P00734 | 5/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3090331 | 0.92 | LARS1 (0.47) | LARS1F2LMNAPOLBGAA | |
| SCHEMBL3090735 | 0.91 | F2 (0.48) | LARS1F2NLRP3NPSR1 | |
| SCHEMBL14999923 | 0.91 | MAPT (0.46) | LARS1F2LMNARAB9ACA2 | |
| SCHEMBL13151776 | 0.90 | LARS1 (0.48) | LARS1F2LMNAPOLBGAA | |
| SCHEMBL18387952 | 0.90 | LARS1 (0.48) | LARS1F2LMNAPOLBGAA | |
| SCHEMBL3093901 | 0.90 | MMP9 (0.46) | LARS1F2LMNARAB9AALDH1A1 | |
| SCHEMBL3090750 | 0.90 | LARS1 (0.45) | LARS1F2LMNAPOLBCA2 | |
| SCHEMBL3102970 | 0.90 | MMP9 (0.46) | LARS1F2LMNARAB9AALDH1A1 | |
| SCHEMBL14999933 | 0.89 | LARS1 (0.47) | LARS1F2LMNAPOLBGAA | |
| SCHEMBL3096834 | 0.89 | LARS1 (0.44) | LARS1F2LMNAPOLBCA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8461209-B2 | Malonic acid sulfonamide derivative and pharmaceutical use thereof | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2013-06-11 | — | — | US | disclosed |