Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LARS1 | Q9P2J5 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | F2 | P00734 | 3/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.43 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.43 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.43 |
| ▸ | PLAU | P00749 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15000007 | 0.92 | HDAC1 (0.49) | LARS1ATMALDH1A1LMNAGAA | |
| SCHEMBL13151776 | 0.91 | LARS1 (0.48) | LARS1ALDH1A1LMNAGAASMN1; SMN2 | |
| SCHEMBL18387952 | 0.91 | LARS1 (0.48) | LARS1ATMALDH1A1LMNAGAA | |
| SCHEMBL15000288 | 0.91 | ALDH1A1 (0.47) | LARS1ATMALDH1A1LMNAGAA | |
| SCHEMBL15000276 | 0.90 | LARS1 (0.53) | LARS1ALDH1A1LMNAF2PLG | |
| SCHEMBL3085973 | 0.90 | LARS1 (0.53) | LARS1ALDH1A1LMNAF2PLG | |
| SCHEMBL14999932 | 0.89 | LARS1 (0.47) | LARS1NPSR1ALDH1A1LMNAGAA | |
| SCHEMBL3090331 | 0.89 | LARS1 (0.47) | LARS1ALDH1A1LMNAGAASMN1; SMN2 | |
| SCHEMBL18383338 | 0.89 | LARS1 (0.50) | LARS1ALDH1A1LMNAGAASMN1; SMN2 | |
| SCHEMBL13152388 | 0.89 | LARS1 (0.50) | LARS1ALDH1A1LMNAGAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8461209-B2 | Malonic acid sulfonamide derivative and pharmaceutical use thereof | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2013-06-11 | — | — | US | disclosed |