SCHEMBL150019

SCHEMBL150019

O=Cc1cc(F)c(F)cc1F

nearest known ligand 0.56

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ERN1 O75460 10/20 0.46
TDP1 Q9NUW8 3/20 0.38
MEN1 O00255 1/20 0.38
LMNA P02545 1/20 0.38
THRB P10828 1/20 0.38
BLM P54132 1/20 0.38
KMT2A Q03164 1/20 0.38
KDM4E B2RXH2 1/20 0.33
ALDH1A1 P00352 1/20 0.33
TSHR P16473 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL28586585 0.97 ERN1 (0.44) ERN1TDP1MEN1LMNATHRB
SCHEMBL248719 0.94 ERN1 (0.50) ERN1TDP1MEN1LMNATHRB
SCHEMBL650978 0.87 ERN1 (0.50) ERN1TDP1MEN1LMNATHRB
SCHEMBL29955962 0.82 ERN1 (0.39) ERN1TDP1MEN1LMNATHRB
SCHEMBL3070038 0.82 ERN1 (0.39) ERN1TDP1MEN1LMNATHRB
SCHEMBL29655114 0.82 ERN1 (0.43) ERN1TDP1MEN1LMNATHRB
SCHEMBL1972414 0.82 TDP1 (0.41) ERN1TDP1MEN1LMNATHRB
SCHEMBL31618920 0.82 TDP1 (0.41) ERN1TDP1MEN1LMNATHRB
SCHEMBL933374 0.82 ERN1 (0.43) ERN1TDP1MEN1LMNATHRB
SCHEMBL26292881 0.82 ERN1 (0.39) ERN1TDP1MEN1LMNATHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 482 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119707807-A Preparation method and application of tacrine derivative 沈阳药科大学 2025-03-28 CN claimed
CN-117143598-B High-entropy carbon quantum dot nanomaterial and preparation method and application thereof 中南大学 2024-11-08 CN claimed
CN-118459422-A Thiazole thiazolinone compound containing multiple halogen atoms and preparation method thereof 南京工业大学 2024-08-09 CN claimed
CN-118459420-A Thiazolinone compound containing multiple halogen atoms and preparation method thereof 南京工业大学 2024-08-09 CN claimed
CN-115611717-B Preparation method of polyfluorobenzaldehyde 上海万溯药业有限公司 2024-06-28 CN claimed
CN-117143598-A High-entropy carbon quantum dot nanomaterial and preparation method and application thereof 中南大学 2023-12-01 CN claimed
CN-116178121-A Preparation method of 2,4, 5-trifluoro-benzaldehyde 浙江巍华新材料股份有限公司 2023-05-30 CN claimed
CN-115677477-B Preparation method of 2,4, 5-trifluoro-phenylacetic acid and intermediate thereof 上海康鹏科技股份有限公司 2023-05-26 CN claimed
CN-115677477-A Preparation method of 2,4, 5-trifluoro-phenylacetic acid and intermediate thereof 上海康鹏科技股份有限公司 2023-02-03 CN claimed
CN-115611717-A Preparation method of polyfluorobenzaldehyde 上海万溯药业有限公司 2023-01-17 CN claimed
CN-103819475-A Synthetic method of sitagliptin and salt thereof ZHEJIANG NHU CO LTD 2014-05-28 CN claimed
CN-103483340-A Synthetic method for sitagliptin WUXI BIORTUS BIOSCIENCES CO LTD 2014-01-01 CN claimed
EP-1472215-A4 (OXIME)CARBAMOYL FATTY ACID AMIDE HYDROLASE INHIBITORS BRISTOL MYERS SQUIBB CO (US) 2007-05-09 EP claimed
US-6949574-B2 (Oxime)carbamoyl fatty acid amide hydrolase inhibitors BRISTOL-MYERS SQUIBB COMPANY (US) 2005-09-27 US claimed
EP-1472215-A2 (OXIME)CARBAMOYL FATTY ACID AMIDE HYDROLASE INHIBITORS Bristol-Myers Squibb Company (US) 2004-11-03 EP claimed
US-20030195226-A1 (Oxime)carbamoyl fatty acid amide hydrolase inhibitors SIT SING-YUEN (US) 2003-10-16 US claimed
WO-2003065989-A2 (OXIME)CARBAMOYL FATTY ACID AMIDE HYDROLASE INHIBITORS BRISTOL-MYERS SQUIBB COMPANY (US) 2003-08-14 WO claimed
EP-0725787-A1 ACTIVATED NUCLEOSIDE PHOSPHORAMIDITES AND METHODS FOR THE PREPARATION AND USE THEREOF BECKMAN INSTRUMENTS, INC. (US) 1996-08-14 EP claimed
WO-1996006853-A1 ACTIVATED NUCLEOSIDE PHOSPHORAMIDITES AND METHODS FOR THE PREPARATION AND USE THEREOF BECKMAN INSTRUMENTS, INC. (US) 1996-03-07 WO claimed
EP-0164619-B1 2,4,5-TRIHALO OR 2,3,4,5-TETRAHALO BENZENE DERIVATIVES AND PROCESS FOR PRODUCING THEM BAYER AG (DE) 1988-10-12 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030195226-A1 (Oxime)carbamoyl fatty acid amide hydrolase inhibitors FAAH, FAAH2, NCEH1 ERN1 4398/4885TDP1 949/4885MEN1 4269/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.