SCHEMBL150034

SCHEMBL150034

CC(C(=O)O)n1c2ccccc2c2ccccc21

nearest known ligand 0.56

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.53
POLB P06746 3/20 0.48
KDM4E B2RXH2 4/20 0.46
HTT P42858 1/20 0.45
USP5 P45974 1/20 0.45
FABP3 P05413 1/20 0.43
FABP4 P15090 1/20 0.43
FABP5 Q01469 1/20 0.43
BCHE P06276 1/20 0.42
ACHE P22303 1/20 0.42
NPY5R Q15761 1/20 0.42
ALDH1A1 P00352 2/20 0.42
MAPT P10636 1/20 0.42
RECQL P46063 1/20 0.42
MEN1 O00255 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18258624 1.00 KMT2A (0.53) KMT2APOLBKDM4EHTTUSP5
SCHEMBL21027730 0.91 P2RX4 (0.50) KMT2APOLBKDM4EHTTUSP5
SCHEMBL16468650 0.87 KMT2A (0.43) KMT2APOLBKDM4EHTTUSP5
SCHEMBL27543263 0.86 TSPO (0.50) KMT2APOLBKDM4ENPY5RALDH1A1
SCHEMBL27841871 0.84 POLB (0.53) KMT2APOLBKDM4EHTTFABP3
SCHEMBL28875485 0.83 LMNA (0.51) KMT2APOLBKDM4EHTTALDH1A1
SCHEMBL27628149 0.82 POLB (0.47) KMT2APOLBKDM4EHTTFABP3
SCHEMBL27984706 0.82 POLB (0.47) KMT2APOLBKDM4EHTTFABP3
SCHEMBL27518137 0.82 KMT2A (0.43) KMT2APOLBKDM4EHTTUSP5
SCHEMBL11826429 0.80 KDM4E (0.51) KMT2APOLBKDM4EHTTUSP5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 77 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100171923-A1 LACTAM POLYMER DERIVATIVES JOHSNON & JOHNSON VISION CARE, INC. 2010-07-08 US claimed
US-20070290174-A1 LACTAM POLYMER DERIVATIVES JOHNSON & JOHNSON VISION CARE, INC. 2007-12-20 US claimed
CN-101065407-A Lactam polymer derivatives JOHNSON & JOHNSON VISION CARE (US) 2007-10-31 CN claimed
EP-1799724-A2 LACTAM POLYMER DERIVATIVES Johnson and Johnson Vision Care, Inc. (US) 2007-06-27 EP claimed
WO-2006039276-A2 LACTAM POLYMER DERIVATIVES JOHNSON & JOHNSON VISION CARE, INC. (US) 2006-04-13 WO claimed
US-20060069235-A1 Lactam polymer derivatives JOHNSON & JOHNSON VISION CARE, INC. 2006-03-30 US claimed
US-20240151996-A1 CHIRAL ORGANIC OPTOELECTRONIC MOLECULES FOR IMPROVED REFRACTIVE INDEX MODULATION IN ACTIVE OPTICAL DEVICES META PLATFORMS TECHNOLOGIES, LLC 2024-05-09 US disclosed
US-20240150935-A1 CHIRAL ORGANIC OPTOELECTRONIC MOLECULES WITH TUNABLE REFRACTIVE INDEX FOR IMPROVED CONTROL OF CIRCULARLY POLARIZED LIGHT PROPAGATION IN OPTICAL DEVICES META PLATFORMS TECHNOLOGIES, LLC 2024-05-09 US disclosed
EP-4361711-A1 CHIRAL ORGANIC OPTOELECTRONIC MOLECULES FOR IMPROVED REFRACTIVE INDEX MODULATION IN ACTIVE OPTICAL DEVICES Meta Platforms Technologies, LLC (US) 2024-05-01 EP disclosed
US-11402560-B2 Method for producing laminated body SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2022-08-02 US disclosed
CN-109765651-B Composite retardation plate, optical laminate, and image display device 住友化学株式会社 2022-05-03 CN disclosed
CN-109765652-B Composite retardation plate, optical laminate, and image display device 住友化学株式会社 2022-03-25 CN disclosed
US-20210116619-A1 METHOD FOR PRODUCING LAMINATED BODY SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2021-04-22 US disclosed
EP-1799724-A2 LACTAM POLYMER DERIVATIVES Johnson and Johnson Vision Care, Inc. (US) 2007-06-27 EP disclosed
CN-1916097-A Adhesive sheet and semiconductor device and process for producing the same HITACHI CHEMICAL CO LTD (JP) 2007-02-21 CN disclosed
CN-1810789-A Prepn of-2-(N-carbazolyl)-ethoxy carbohydrazide DALIAN CHEMICAL PHYSICS INST (CN) 2006-08-02 CN disclosed
WO-2006039276-A2 LACTAM POLYMER DERIVATIVES JOHNSON & JOHNSON VISION CARE, INC. (US) 2006-04-13 WO disclosed
US-20060069235-A1 Lactam polymer derivatives JOHNSON & JOHNSON VISION CARE, INC. 2006-03-30 US disclosed
CN-1633487-A Adhesive sheet, semiconductor device and method for manufacturing the same HITACHI CHEMICAL CO LTD (JP) 2005-06-29 CN disclosed
CN-1230178-A Polydithiocarbamate-containing macromolecules and use thereof for therapeutic and diagnostic applications MEDINOX INC (US) 1999-09-29 CN disclosed