SCHEMBL15003434

SCHEMBL15003434

Cc1ccccc1Sc1c(F)ccc2ccccc12

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.42
CYP2A6 P11509 4/20 0.42
TSHR P16473 4/20 0.40
CYP1A2 P05177 3/20 0.40
HSD17B10 Q99714 3/20 0.39
HPGD P15428 2/20 0.39
HAO1 Q9UJM8 1/20 0.38
HPRT1 P00492 2/20 0.37
USP2 O75604 1/20 0.37
PAK1 Q13153 1/20 0.37
ACHE P22303 1/20 0.36
IDO1 P14902 1/20 0.36
TDP1 Q9NUW8 1/20 0.35
AR P10275 1/20 0.34
MAPK1 P28482 2/20 0.33
IFNAR1 P17181 1/20 0.33
CYP3A4 P08684 1/20 0.33
CASP1 P29466 1/20 0.33
RAB9A P51151 1/20 0.33
CASP7 P55210 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15003445 0.80 ALDH1A1 (0.42) ALDH1A1CYP2A6TSHRCYP1A2HSD17B10
SCHEMBL16218708 0.80 HPRT1 (0.37) ALDH1A1CYP2A6TSHRCYP1A2HSD17B10
SCHEMBL31323122 0.74 CYP2A6 (0.44) ALDH1A1CYP2A6TSHRCYP1A2HSD17B10
SCHEMBL19901855 0.74 CYP2A6 (0.44) ALDH1A1CYP2A6TSHRCYP1A2HSD17B10
SCHEMBL15003462 0.74 ALDH1A1 (0.50) ALDH1A1TSHRHPGDHPRT1TDP1
SCHEMBL9488226 0.71 HAO1 (0.47) ALDH1A1CYP2A6TSHRCYP1A2HAO1
SCHEMBL2154633 0.70 ACHE (0.54) ALDH1A1TSHRHAO1ACHEIDO1
SCHEMBL577640 0.70 CYP2A6 (0.58) ALDH1A1CYP2A6TSHRCYP1A2HSD17B10
SCHEMBL576094 0.69 ACHE (0.53) ALDH1A1CYP2A6TSHRCYP1A2HAO1
SCHEMBL11765384 0.68 ALDH1A1 (0.47) ALDH1A1CYP2A6TSHRCYP1A2HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2013081315-A1 COMPOUND FOR ORGANIC ELECTRONIC DEVICE, ORGANIC ELECTRONIC DEVICE COMPRISING SAME AND ELECTRONIC DEVICE COMPRISING THE ORGANIC ELECTRONIC DEVICE 덕산하이메탈(주) (KR) 2013-06-06 WO disclosed