Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 3/20 | 0.63 |
| ▸ | ECE1 | P42892 | 7/20 | 0.59 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | MPO | P05164 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | BLM | P54132 | 1/20 | 0.58 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5822565 | 0.99 | ACE (0.64) | ACEECE1ERAP2ALOX15KDM4E | |
| SCHEMBL5970197 | 0.99 | ACE (0.64) | ACEECE1ERAP2ALOX15KDM4E | |
| SCHEMBL1898083 | 0.99 | ACE (0.64) | ACEECE1ERAP2ALOX15KDM4E | |
| SCHEMBL3053752 | 0.99 | ACE (0.64) | ACEECE1ERAP2ALOX15KDM4E | |
| SCHEMBL5735540 | 0.99 | ACE (0.64) | ACEECE1ERAP2ALOX15KDM4E | |
| SCHEMBL30997441 | 0.96 | ACE (0.61) | ACEECE1ERAP2ALOX15KDM4E | |
| SCHEMBL30903469 | 0.94 | ERAP2 (0.60) | ACEECE1ERAP2ALOX15KDM4E | |
| SCHEMBL17941661 | 0.93 | LTA4H (0.59) | ACEERAP2KMT2A | |
| SCHEMBL17941660 | 0.93 | LTA4H (0.59) | ACEERAP2KMT2A | |
| SCHEMBL30284429 | 0.93 | ERAP2 (0.64) | ACEECE1ERAP2ALOX15KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2601963-B1 | N-ISOVALEROYL-L-GLUTAMYL-L-TRYPTOPHAN AS AN AGENT INHIBITING THE FORMATION OF ULCERS IN THE STOMACH AND THE DUODENUM | OBSHESTVO S OGRANICHENNOJ OTVETSTVENNOSTJU CYTONIR (RU) | 2015-04-22 | — | — | EP | disclosed |
| EP-2601963-A1 | N-ISOVALEROYL-L-GLUTAMYL-L-TRYPTOPHAN AS AN AGENT INHIBITING THE FORMATION OF ULCERS IN THE STOMACH AND THE DUODENUM | Obshestvo S Ogranichennoj Otvetstvennostju "citoNIR" (RU) | 2013-06-12 | — | — | EP | disclosed |