SCHEMBL1898083

SCHEMBL1898083

NC(=O)CC[C@H](N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)O

nearest known ligand 0.64

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ ACE P12821 3/20 0.64
▸ ECE1 P42892 7/20 0.60
▸ ERAP2 Q6P179 1/20 0.59
▸ ALOX15 P16050 1/20 0.59
▸ KDM4E B2RXH2 1/20 0.59
▸ MEN1 O00255 1/20 0.59
▸ LMNA P02545 1/20 0.59
▸ MPO P05164 1/20 0.59
▸ MAPT P10636 1/20 0.59
▸ TSHR P16473 1/20 0.59
▸ BLM P54132 1/20 0.59
▸ PMP22 Q01453 1/20 0.59
▸ KMT2A Q03164 1/20 0.59
▸ HIF1A Q16665 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5822565 1.00 ACE (0.64) ACEECE1ERAP2ALOX15KDM4E
SCHEMBL5970197 1.00 ACE (0.64) ACEECE1ERAP2ALOX15KDM4E
SCHEMBL5735540 1.00 ACE (0.64) ACEECE1ERAP2ALOX15KDM4E
SCHEMBL3053752 1.00 ACE (0.64) ACEECE1ERAP2ALOX15KDM4E
SCHEMBL15004878 0.99 ACE (0.63) ACEECE1ERAP2ALOX15KDM4E
SCHEMBL30997441 0.97 ACE (0.61) ACEECE1ERAP2ALOX15KDM4E
SCHEMBL30903469 0.95 ERAP2 (0.60) ACEECE1ERAP2ALOX15KDM4E
SCHEMBL17941661 0.94 LTA4H (0.59) ACEERAP2KMT2A
SCHEMBL17941660 0.94 LTA4H (0.59) ACEERAP2KMT2A
SCHEMBL30284429 0.94 ERAP2 (0.64) ACEECE1ERAP2ALOX15KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 133 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3987064-A1 METHOD FOR DIAGNOSING ESTHETIC DEGRADATIONS OF SKIN L'OREAL (FR) 2022-04-27 — — EP claimed
WO-2020260355-A1 METHOD FOR DIAGNOSING ESTHETIC DEGRADATIONS OF SKIN L'OREAL (FR) 2020-12-30 — — WO claimed
WO-2012068412-A2 METHOD AND COMPOSITIONS FOR TREATMENT OF STAT3-RESPONSIVE CANCERS AND/OR RENAL CANCER SCICLONE PHARMACEUTICALS, INC. (US) 2012-05-24 — — WO claimed
EP-1814566-B1 TREATMENT OR PREVENTION OF HEMORRHAGIC VIRAL INFECTIONS WITH IMMUNOMODULATOR COMPOUNDS SCICLONE PHARMACEUTICALS INC (US) 2010-07-28 — — EP claimed
US-20030087830-A1 Low molecular weight components of cartilage, complexes of metals with amino acids, DI-peptides and analogs thereof; processes for preparation and therapeutic uses thereof AETERNA ZENTARIS INC. (CA) 2003-05-08 — — US claimed
WO-2002100421-A1 LOW MOLECULAR WEIGHT COMPONENTS OF CARTILAGE, COMPLEXES OF COPPER WITH AMINO ACIDS OR DI-PEPTIDES; PROCESSES FOR PREPARATION AND THERAPEUTIC USES THEREOF LES LABORATOIRES AETERNA INC. (CA) 2002-12-19 — — WO claimed
WO-1998009989-A1 THE USE OF MURAMYLPEPTIDES IN THE TREATMENT OF MYELOSUPPRESSED OR OTHERWISE IMMUNOCOMPROMISED STATES PEPTECH (UK) LIMITED (GB) 1998-03-12 — — WO claimed
EP-0722332-A1 COMPOUNDS FOR MEDICINAL USE PEPTECH (UK) LIMITED (GB) 1996-07-24 — — EP claimed
WO-1995010293-A1 COMPOUNDS FOR MEDICINAL USE PEPTECH (UK) LIMITED (GB) 1995-04-20 — — WO claimed
EP-0457314-A1 Nutrient compositions containing peptides CLINTEC NUTRITION COMPANY (US) 1991-11-21 — — EP claimed
JP-6078687-A — — None — — JP disclosed
WO-2026086694-A1 PEDIATRIC COMPOUND AMINO ACID INJECTION AND PREPARATION METHOD THEREFOR 四川科伦药业股份有限公司 2026-04-30 — — WO disclosed
EP-3604503-B1 ADDITIVE FOR UNDIFFERENTIATION MAINTAINING MEDIUM AJINOMOTO KK (JP) 2026-03-18 — — EP disclosed
US-20250270512-A1 ADDITIVE FOR UNDIFFERENTIATION MAINTAINING MEDIUM AJINOMOTO CO., INC. (JP) 2025-08-28 — — US disclosed
US-12383628-B2 Hydrogel-forming composition for controlled release VRIJE UNIVERSITEIT BRUSSEL (BE) 2025-08-12 — — US disclosed
US-5744452-A IMMUNE SYSTEM DISORDERS, AIDS Wei, Edward T. (US) 1998-04-28 — — US disclosed
US-5728680-A ADMINISTERING GLUTAMIC ACID-TRYPTOPHAN DIPEPTIDE; IMMUNOMODULATION CYTOVEN J.V. (US) 1998-03-17 — — US disclosed
WO-1997019691-A1 GAMMA-L-GLUTAMYL CONTAINING IMMUNOMODULATOR COMPOUNDS AND METHODS THEREWITH WEI, EDWARD, T. (US) 1997-06-05 — — WO disclosed
WO-1995003067-A1 PHARMACEUTICAL WITH IMMUNOMODULATING ACTIVITY KHAVINSON VLADIMIR KHATSKELEVI (RU) 1995-02-02 — — WO disclosed
JP-H0678687-A FEED FOR CRUSTACEANS NKK CORP 1994-03-22 — — JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030087830-A1 Low molecular weight components of cartilage, complexes of metals with amino acids, DI-peptides and analogs thereof; processes for preparation and therapeutic uses thereof TIE1, TEK, VEGFA ACE 1848/4885ECE1 830/4885ERAP2 549/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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