SCHEMBL1500604

SCHEMBL1500604

CN1C(=O)c2cccc(Cl)c2C1=O

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.56
HPGD P15428 4/20 0.56
KDM4E B2RXH2 4/20 0.56
MEN1 O00255 6/20 0.53
KMT2A Q03164 6/20 0.53
USP2 O75604 3/20 0.53
CASP1 P29466 2/20 0.53
BRCA1 P38398 1/20 0.53
CASP7 P55210 1/20 0.53
CASP3 P42574 1/20 0.48
MAPT P10636 2/20 0.47
POLB P06746 2/20 0.44
KEAP1 Q14145 2/20 0.43
NFE2L2 Q16236 2/20 0.43
ATM Q13315 1/20 0.43
GAA P10253 1/20 0.43
TYMS P04818 2/20 0.42
HTT P42858 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
PRMT1 Q99873 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30725966 1.00 ALDH1A1 (0.56) ALDH1A1HPGDKDM4EMEN1KMT2A
SCHEMBL14463508 0.79 KDM4E (0.59) ALDH1A1HPGDKDM4EMEN1KMT2A
SCHEMBL454552 0.78 KDM4E (0.41) ALDH1A1HPGDKDM4EMEN1KMT2A
SCHEMBL13239551 0.78 MEN1 (0.54) ALDH1A1HPGDKDM4EMEN1KMT2A
SCHEMBL2036747 0.78 MEN1 (0.58) ALDH1A1HPGDKDM4EMEN1KMT2A
SCHEMBL9436896 0.77 KDM4E (0.47) ALDH1A1HPGDKDM4EMEN1KMT2A
SCHEMBL30788074 0.76 ANPEP (0.54) ALDH1A1HPGDKDM4EMEN1KMT2A
SCHEMBL133067 0.76 MEN1 (0.53) ALDH1A1HPGDKDM4EMEN1KMT2A
SCHEMBL3218263 0.76 ANPEP (0.54) ALDH1A1HPGDKDM4EMEN1KMT2A
SCHEMBL30725967 0.76 MEN1 (0.53) ALDH1A1HPGDKDM4EMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 159 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119504556-A Bisphenol phthaloyl Process for producing imine 潍坊弘润石化科技有限公司 2025-02-25 CN claimed
CN-116283856-B Preparation method of 3,4' -oxydiphthalic anhydride 大连新阳光材料科技有限公司 2024-08-23 CN claimed
CN-116283856-A Preparation method of 3,4' -oxydiphthalic anhydride 大连新阳光材料科技有限公司 2023-06-23 CN claimed
CN-113754621-B Synthesis method of 2,3',3,4' -diphenyl sulfone tetracarboxylic dianhydride 常州市阳光药业有限公司 2023-06-23 CN claimed
CN-115819318-A Tetrafluorobenzoic acid intermediate impurity and preparation method thereof 浙江司太立制药股份有限公司 2023-03-21 CN claimed
CN-113754621-A Method for synthesizing 2,3',3,4' -diphenyl sulfone tetracarboxylic dianhydride 常州市阳光药业有限公司 2021-12-07 CN claimed
EP-1660560-B1 PHASE TRANSFER CATALYZED METHOD FOR PREPARATION OF POLYETEHRIMIDES SABIC GLOBAL TECHNOLOGIES BV (NL) 2016-03-23 EP claimed
CN-101704950-B PASSI terpolymer and preparation method thereof NINGBO INST MAT TECH & ENG CAS 2013-07-31 CN claimed
EP-2233512-B1 POLYTHIOETHERIMIDES AND METHOD FOR PRODUCING THEREOF NINGBO INST MATERIALS TECHNOLOGY & ENG CAS (CN) 2013-03-20 EP claimed
CN-102030903-B Preparation method of polythioether ketone imide terpolymer NINGBO INST MAT TECH & ENG CAS 2013-03-06 CN claimed
EP-1660556-A1 COPOLYETHERIMIDES GENERAL ELECTRIC COMPANY (US) 2006-05-31 EP claimed
EP-1660560-A2 PHASE TRANSFER CATALYZED METHOD FOR PREPARATION OF POLYETEHRIMIDES GENERAL ELECTRIC COMPANY (US) 2006-05-31 EP claimed
WO-2005052029-A2 POLYETHERSULFONE COMPOSITION, METHOD OF MAKING AND ARTICLES THEREFROM GENERAL ELECTRIC COMPANY (US) 2005-06-09 WO claimed
US-20050113558-A1 Polyethersulfone composition, method of making and articles therefrom GENERAL ELECTRIC COMPANY 2005-05-26 US claimed
WO-2005023901-A1 COPOLYETHERIMIDES GENERAL ELECTRIC COMPANY (US) 2005-03-17 WO claimed
WO-2005021618-A2 PHASE TRANSFER CATALYZED METHOD FOR PREPARATION OF POLYETEHRIMIDES GENERAL ELECTRIC COMPANY (US) 2005-03-10 WO claimed
US-20050049390-A1 Phase transfer catalyzed method for preparation of polyetherimides GENERAL ELECTRIC COMPANY 2005-03-03 US claimed
US-6849706-B1 Copolyetherimides GENERAL ELECTRIC COMPANY (US) 2005-02-01 US claimed
EP-0172298-B1 METHOD FOR MAKING THIOETHER(BISPHTHALIMIDE)S GENERAL ELECTRIC COMPANY (US) 1991-09-11 EP claimed
EP-0172298-A2 Method for making thioether(bisphthalimide)s GENERAL ELECTRIC COMPANY (US) 1986-02-26 EP claimed