Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAA50 | Q9GZZ1 | 2/20 | 0.86 |
| ▸ | CHAT | P28329 | 2/20 | 0.82 |
| ▸ | EP300 | Q09472 | 4/20 | 0.81 |
| ▸ | KAT5 | Q92993 | 2/20 | 0.81 |
| ▸ | AURKA | O14965 | 2/20 | 0.81 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.81 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.76 |
| ▸ | NAA40 | Q86UY6 | 1/20 | 0.71 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28115993 | 1.00 | NAA50 (0.86) | NAA50CHATEP300KAT5AURKA | |
| SCHEMBL22590110 | 0.98 | NAA50 (0.85) | NAA50CHATEP300KAT5AURKA | |
| SCHEMBL2933622 | 0.95 | NAA50 (0.87) | NAA50CHATEP300KAT5AURKA | |
| SCHEMBL849827 | 0.95 | NAA50 (0.87) | NAA50CHATEP300KAT5AURKA | |
| SCHEMBL29424596 | 0.95 | NAA50 (0.87) | NAA50CHATEP300KAT5AURKA | |
| SCHEMBL4287977 | 0.95 | NAA50 (0.87) | NAA50CHATEP300KAT5AURKA | |
| SCHEMBL19554420 | 0.95 | NAA50 (0.87) | NAA50CHATEP300KAT5AURKA | |
| SCHEMBL22556110 | 0.95 | NAA50 (0.87) | NAA50CHATEP300KAT5AURKA | |
| SCHEMBL18925864 | 0.95 | NAA50 (0.87) | NAA50CHATEP300KAT5AURKA | |
| SCHEMBL59962 | 0.95 | NAA50 (0.87) | NAA50CHATEP300KAT5AURKA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2791342-A1 | MODIFIED MICROORGANISMS AND METHODS OF MAKING BUTADIENE USING SAME | Braskem S.A. (BR) | 2014-10-22 | — | — | EP | disclosed |
| WO-2013192183-A1 | MODIFIED MICROORGANISMS AND METHODS OF CO-PRODUCING BUTADIENE WITH 1-PROPANOL AND/OR 1,2-PROPANEDIOL | BRASKEM S/A AP 09 (BR) | 2013-12-27 | — | — | WO | disclosed |
| WO-2013090915-A1 | MODIFIED MICROORGANISMS AND METHODS OF MAKING BUTADIENE USING SAME | BRASKEM S.A. (BR) | 2013-06-20 | — | — | WO | disclosed |