Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAA50 | Q9GZZ1 | 2/20 | 0.87 |
| ▸ | CHAT | P28329 | 2/20 | 0.83 |
| ▸ | EP300 | Q09472 | 3/20 | 0.82 |
| ▸ | KAT5 | Q92993 | 2/20 | 0.82 |
| ▸ | AURKA | O14965 | 2/20 | 0.82 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.82 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.73 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29530678 | 1.00 | NAA50 (0.87) | NAA50CHATEP300KAT5AURKA | |
| SCHEMBL22556110 | 1.00 | NAA50 (0.87) | NAA50CHATEP300KAT5AURKA | |
| SCHEMBL15299842 | 0.98 | NAA50 (0.86) | NAA50CHATEP300KAT5AURKA | |
| SCHEMBL19693052 | 0.98 | NAA50 (0.86) | NAA50CHATEP300KAT5AURKA | |
| SCHEMBL29396999 | 0.98 | NAA50 (0.85) | NAA50CHATEP300KAT5AURKA | |
| SCHEMBL284786 | 0.98 | NAA50 (0.85) | NAA50CHATEP300KAT5AURKA | |
| SCHEMBL28041178 | 0.98 | NAA50 (0.85) | NAA50CHATEP300KAT5AURKA | |
| SCHEMBL18918369 | 0.98 | NAA50 (0.85) | NAA50CHATEP300KAT5AURKA | |
| SCHEMBL28216089 | 0.98 | NAA50 (0.85) | NAA50CHATEP300KAT5AURKA | |
| SCHEMBL59721 | 0.97 | NAA50 (0.88) | NAA50CHATEP300KAT5AURKA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 252 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260035705-A1 | ENGINEERED MICROORGANISMS WITH G3P ->3PG ENZYME AND/OR FRUCTOSE-1,6-BISPHOSPHATASE INCLUDING THOSE HAVING SYNTHETIC OR ENHANCED METHYLOTROPHY | AGAIN BIO APS (DK) | 2026-02-05 | — | — | US | claimed |
| US-12529078-B2 | Microorganisms and methods for improving product yields on methanol using acetyl-CoA synthesis | GENOMATICA, INC. (US) | 2026-01-20 | — | — | US | claimed |
| US-20250084387-A1 | FORMATE DEHYDROGENASE VARIANTS AND METHODS OF USE | AGAIN BIO APS (DK) | 2025-03-13 | — | — | US | claimed |
| US-20240294950-A1 | MICROORGANISMS AND METHODS FOR IMPROVING PRODUCT YIELDS ON METHANOL USING ACETYL-COA SYNTHESIS | AGAIN BIO APS (DK) | 2024-09-05 | — | — | US | claimed |
| US-20240218346-A1 | PHOSPHOKETOLASE VARIANTS AND METHODS OF USE | AGAIN BIO APS (DK) | 2024-07-04 | — | — | US | claimed |
| EP-4296364-A2 | MICROORGANISMS AND METHODS FOR IMPROVING PRODUCT YIELDS ON METHANOL USING ACETYL-COA SYNTHESIS | Genomatica, Inc. (US) | 2023-12-27 | — | — | EP | claimed |
| EP-3967747-B1 | MICROORGANISMS AND METHODS FOR IMPROVING PRODUCT YIELDS ON METHANOL USING ACETYL-COA SYNTHESIS | GENOMATICA INC (US) | 2023-11-08 | — | — | EP | claimed |
| CN-116615549-A | Recombinant microorganism and use thereof | 朗泽科技有限公司 | 2023-08-18 | — | — | CN | claimed |
| US-20230126921-A1 | NON-NATURAL MICROBIAL ORGANISMS WITH IMPROVED ENERGETIC EFFICIENCY | AGAIN BIO APS (DK) | 2023-04-27 | — | — | US | claimed |
| WO-2022217064-A2 | PHOSPHOKETOLASE VARIANTS AND METHODS OF USE | GENOMATICA, INC. (US) | 2022-10-13 | — | — | WO | claimed |
| US-20170159075-A1 | MICROORGANISMS AND METHODS FOR IMPROVING PRODUCT YIELDS ON METHANOL USING ACETYL-COA SYNTHESIS | AGAIN BIO APS (DK) | 2017-06-08 | — | — | US | claimed |
| US-20160340699-A1 | TYPE II FATTY ACID SYNTHESIS ENZYMES IN REVERSE ß-OXIDATION | NATIONAL SCIENCE FOUNDATION | 2016-11-24 | — | — | US | claimed |
| EP-3077501-A1 | MICROORGANISMS AND METHODS FOR IMPROVING PRODUCT YIELDS ON METHANOL USING ACETYL-COA SYNTHESIS | Genomatica, Inc. (US) | 2016-10-12 | — | — | EP | claimed |
| WO-2016044713-A1 | NON-NATURAL MICROBIAL ORGANISMS WITH IMPROVED ENERGETIC EFFICIENCY | GENOMATICA, INC. (US) | 2016-03-24 | — | — | WO | claimed |
| WO-2016007258-A9 | OMEGA-AMINATED CARBOXYLIC ACIDS | WILLIAM MARCH RICE UNIVERSITY (US) | 2016-03-10 | — | — | WO | claimed |
| WO-2016007258-A1 | OMEGA-AMINATED CARBOXYLIC ACIDS | WILLIAM MARCH RICE UNIVERSITY (US) | 2016-01-14 | — | — | WO | claimed |
| US-9175297-B2 | Microorganisms for the production of 1,4-Butanediol | GENOMATICA, INC. (US) | 2015-11-03 | — | — | US | claimed |
| WO-2015084633-A1 | MICROORGANISMS AND METHODS FOR IMPROVING PRODUCT YIELDS ON METHANOL USING ACETYL-COA SYNTHESIS | GENOMATICA, INC. (US) | 2015-06-11 | — | — | WO | claimed |
| US-20140273110-A1 | FUNCTIONALIZED CARBOXYLIC ACIDS AND ALCOHOLS BY REVERSE FATTY ACID OXIDATION | WILLIAM MARSH RICE UNIVERSITY (US) | 2014-09-18 | — | — | US | claimed |
| WO-2012177943-A1 | MICROORGANISMS FOR PRODUCING 1,4-BUTANEDIOL AND METHODS RELATED THERETO | GENOMATICA, INC. (US) | 2012-12-27 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12529078-B2 | Microorganisms and methods for improving product yields on methanol using acetyl-CoA synthesis | ALDOA, FDPS, DERA | NAA50 298/4885CHAT 1363/4885EP300 1390/4885 |
| US-20260035705-A1 | ENGINEERED MICROORGANISMS WITH G3P ->3PG ENZYME AND/OR FRUCTOSE-1,6-BISPHOSPHATASE INCLUDING THOSE HAVING SYNTHETIC OR ENHANCED METHYLOTROPHY | ME1, FBP1, ME3 | NAA50 2772/4885CHAT 1142/4885EP300 3078/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.