SCHEMBL15020148

SCHEMBL15020148

Nc1ccc(/N=C2\C=C(Nc3ccc(N)cc3)C(=O)C=C2Nc2ccc(N)cc2)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DNM1 Q05193 1/20 0.46
L3MBTL1 Q9Y468 6/20 0.35
BLM P54132 5/20 0.35
CASP3 P42574 4/20 0.35
SENP8 Q96LD8 4/20 0.35
SENP7 Q9BQF6 4/20 0.35
SENP6 Q9GZR1 4/20 0.35
MEN1 O00255 3/20 0.35
KMT2A Q03164 3/20 0.35
APAF1 O14727 3/20 0.35
TDP2 O95551 2/20 0.35
NSD2 O96028 2/20 0.35
POLB P06746 2/20 0.35
SAE1 Q9UBE0 2/20 0.35
UBA2 Q9UBT2 2/20 0.35
GALK1 P51570 1/20 0.35
PPP1CA P62136 1/20 0.35
MAPT P10636 8/20 0.35
HTT P42858 4/20 0.35
ALDH1A1 P00352 3/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15039674 1.00 DNM1 (0.46) DNM1L3MBTL1BLMCASP3SENP8
SCHEMBL15020149 1.00 DNM1 (0.46) DNM1L3MBTL1BLMCASP3SENP8
SCHEMBL15039542 0.94 MAPT (0.46) DNM1L3MBTL1BLMCASP3SENP8
SCHEMBL15020196 0.93 MAPT (0.43) DNM1L3MBTL1BLMCASP3SENP8
SCHEMBL15039805 0.93 MAPT (0.43) DNM1L3MBTL1BLMCASP3SENP8
SCHEMBL15039559 0.91 DNM1 (0.41) DNM1L3MBTL1BLMCASP3SENP8
SCHEMBL15039505 0.89 DNM1 (0.41) DNM1L3MBTL1BLMCASP3SENP8
SCHEMBL10046653 0.89 DNM1 (0.41) DNM1L3MBTL1BLMCASP3SENP8
SCHEMBL11140390 0.89 DNM1 (0.38) DNM1L3MBTL1BLMCASP3SENP8
SCHEMBL17253352 0.87 DNM1 (0.52) DNM1L3MBTL1BLMCASP3SENP8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2791252-A1 TRIAROMATIC AZOMETHINE DIRECT DYES, DYE COMPOSITION COMPRISING AT LEAST ONE SUCH DYE, METHOD OF IMPLEMENTATION AND USE L'OREAL (FR) 2014-10-22 EP claimed
WO-2013087768-A1 TRIAROMATIC AZOMETHINE DIRECT DYES, DYE COMPOSITION COMPRISING AT LEAST ONE SUCH DYE, METHOD OF IMPLEMENTATION AND USE L'OREAL (FR) 2013-06-20 WO claimed
EP-2791252-A1 TRIAROMATIC AZOMETHINE DIRECT DYES, DYE COMPOSITION COMPRISING AT LEAST ONE SUCH DYE, METHOD OF IMPLEMENTATION AND USE L'OREAL (FR) 2014-10-22 EP disclosed
WO-2013087768-A1 TRIAROMATIC AZOMETHINE DIRECT DYES, DYE COMPOSITION COMPRISING AT LEAST ONE SUCH DYE, METHOD OF IMPLEMENTATION AND USE L'OREAL (FR) 2013-06-20 WO disclosed