SCHEMBL15020196

SCHEMBL15020196

Cc1ccc(NC2=CC(=O)C(Nc3ccc(N)cc3)=CC2=Nc2ccc(N)cc2)cc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 0.43
L3MBTL1 Q9Y468 6/20 0.43
KDM4E B2RXH2 3/20 0.43
BLM P54132 3/20 0.43
POLB P06746 3/20 0.43
TDP2 O95551 3/20 0.43
CASP3 P42574 3/20 0.43
SENP8 Q96LD8 3/20 0.43
SENP7 Q9BQF6 3/20 0.43
SENP6 Q9GZR1 3/20 0.43
ALDH1A1 P00352 3/20 0.43
HTT P42858 3/20 0.43
LMNA P02545 2/20 0.43
MAPK1 P28482 2/20 0.43
NSD2 O96028 2/20 0.43
HPGD P15428 2/20 0.43
TP53 P04637 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
DNM1 Q05193 1/20 0.41
MEN1 O00255 5/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15039805 1.00 MAPT (0.43) MAPTL3MBTL1KDM4EBLMPOLB
SCHEMBL17253352 0.94 DNM1 (0.52) MAPTL3MBTL1KDM4EBLMPOLB
SCHEMBL15020149 0.93 DNM1 (0.46) MAPTL3MBTL1KDM4EBLMPOLB
SCHEMBL15020148 0.93 DNM1 (0.46) MAPTL3MBTL1KDM4EBLMPOLB
SCHEMBL15039674 0.93 DNM1 (0.46) MAPTL3MBTL1KDM4EBLMPOLB
SCHEMBL15039559 0.88 DNM1 (0.41) MAPTL3MBTL1KDM4EBLMPOLB
SCHEMBL15039542 0.88 MAPT (0.46) MAPTL3MBTL1KDM4EBLMPOLB
SCHEMBL15019783 0.86 DNM1 (0.59) MAPTL3MBTL1KDM4EBLMPOLB
SCHEMBL15019784 0.86 DNM1 (0.59) MAPTL3MBTL1KDM4EBLMPOLB
SCHEMBL15039496 0.86 DNM1 (0.59) MAPTL3MBTL1KDM4EBLMPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2791252-A1 TRIAROMATIC AZOMETHINE DIRECT DYES, DYE COMPOSITION COMPRISING AT LEAST ONE SUCH DYE, METHOD OF IMPLEMENTATION AND USE L'OREAL (FR) 2014-10-22 EP claimed
WO-2013087768-A1 TRIAROMATIC AZOMETHINE DIRECT DYES, DYE COMPOSITION COMPRISING AT LEAST ONE SUCH DYE, METHOD OF IMPLEMENTATION AND USE L'OREAL (FR) 2013-06-20 WO claimed
EP-2791252-A1 TRIAROMATIC AZOMETHINE DIRECT DYES, DYE COMPOSITION COMPRISING AT LEAST ONE SUCH DYE, METHOD OF IMPLEMENTATION AND USE L'OREAL (FR) 2014-10-22 EP disclosed
WO-2013087768-A1 TRIAROMATIC AZOMETHINE DIRECT DYES, DYE COMPOSITION COMPRISING AT LEAST ONE SUCH DYE, METHOD OF IMPLEMENTATION AND USE L'OREAL (FR) 2013-06-20 WO disclosed