⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15809379 | 0.81 | — | — | |
| SCHEMBL18059962 | 0.81 | MEN1 (0.41) | — | |
| SCHEMBL22770977 | 0.81 | NOS3 (0.33) | — | |
| SCHEMBL1134009 | 0.81 | NOS3 (0.33) | — | |
| SCHEMBL4734335 | 0.81 | MEN1 (0.41) | — | |
| SCHEMBL17841798 | 0.81 | NOS3 (0.33) | — | |
| SCHEMBL23754647 | 0.79 | NOS3 (0.33) | — | |
| SCHEMBL22588782 | 0.77 | HSD17B10 (0.43) | — | |
| SCHEMBL25289772 | 0.77 | TSHR (0.35) | — | |
| SCHEMBL7626489 | 0.72 | TSHR (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2790731-A2 | FGFR-BINDER-ACTIVE AGENT CONJUGATES | Seattle Genetics, Inc. (US) | 2014-10-22 | — | — | EP | disclosed |
| WO-2013087716-A2 | NEW ANTIBODY DRUG CONJUGATES (ADCS) AND THE USE THEREOF | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2013-06-20 | — | — | WO | disclosed |