Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR2 | P25025 | 5/20 | 0.37 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.37 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.37 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 2/20 | 0.34 |
| ▸ | STK10 | O94804 | 1/20 | 0.34 |
| ▸ | SLK | Q9H2G2 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 3/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15020193 | 1.00 | CXCR2 (0.37) | CXCR2TXNRD1TXNRD3TXNRD2PTGS1 | |
| SCHEMBL15019821 | 0.88 | TXNRD1 (0.35) | CXCR2TXNRD1TXNRD3TXNRD2PTGS1 | |
| SCHEMBL15019820 | 0.88 | TXNRD1 (0.35) | CXCR2TXNRD1TXNRD3TXNRD2PTGS1 | |
| SCHEMBL15039543 | 0.82 | DNM1 (0.40) | CXCR2PTGS1PTGS2GSK3BSTK10 | |
| SCHEMBL15020162 | 0.79 | CYP3A4 (0.36) | CXCR2GSK3BSTK10SLKHTT | |
| SCHEMBL15020160 | 0.79 | CYP3A4 (0.36) | CXCR2GSK3BSTK10SLKHTT | |
| SCHEMBL15020067 | 0.75 | DNM1 (0.42) | PTGS1PTGS2GSK3BSTK10SLK | |
| SCHEMBL15039580 | 0.75 | DNM1 (0.42) | PTGS1PTGS2GSK3BSTK10SLK | |
| SCHEMBL15020065 | 0.75 | DNM1 (0.42) | PTGS1PTGS2GSK3BSTK10SLK | |
| SCHEMBL15039793 | 0.72 | DNM1 (0.40) | CXCR2PTGS1PTGS2GSK3BSTK10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2791252-A1 | TRIAROMATIC AZOMETHINE DIRECT DYES, DYE COMPOSITION COMPRISING AT LEAST ONE SUCH DYE, METHOD OF IMPLEMENTATION AND USE | L'OREAL (FR) | 2014-10-22 | — | — | EP | disclosed |
| WO-2013087768-A1 | TRIAROMATIC AZOMETHINE DIRECT DYES, DYE COMPOSITION COMPRISING AT LEAST ONE SUCH DYE, METHOD OF IMPLEMENTATION AND USE | L'OREAL (FR) | 2013-06-20 | — | — | WO | disclosed |