Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 4/20 | 0.45 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 10/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 9/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 7/20 | 0.38 |
| ▸ | LMNA | P02545 | 6/20 | 0.38 |
| ▸ | RAB9A | P51151 | 6/20 | 0.38 |
| ▸ | HPGD | P15428 | 5/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.38 |
| ▸ | HTT | P42858 | 5/20 | 0.38 |
| ▸ | POLB | P06746 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.38 |
| ▸ | NPC1 | O15118 | 4/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.38 |
| ▸ | RECQL | P46063 | 2/20 | 0.38 |
| ▸ | NSD2 | O96028 | 2/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15020218 | 1.00 | IDO1 (0.45) | IDO1NR4A1MAPTL3MBTL1ALDH1A1 | |
| SCHEMBL16426689 | 0.88 | IDO1 (0.43) | IDO1NR4A1MAPTL3MBTL1ALDH1A1 | |
| SCHEMBL15019822 | 0.87 | MAPT (0.52) | IDO1MAPTL3MBTL1ALDH1A1MAPK1 | |
| SCHEMBL15019818 | 0.87 | MAPT (0.52) | IDO1MAPTL3MBTL1ALDH1A1MAPK1 | |
| SCHEMBL15019799 | 0.81 | IDO1 (0.40) | IDO1MAPTL3MBTL1ALDH1A1MAPK1 | |
| SCHEMBL15019795 | 0.81 | IDO1 (0.40) | IDO1MAPTL3MBTL1ALDH1A1MAPK1 | |
| SCHEMBL15020330 | 0.79 | IDO1 (0.39) | IDO1MAPTL3MBTL1ALDH1A1MAPK1 | |
| SCHEMBL15019794 | 0.79 | IDO1 (0.39) | IDO1MAPTL3MBTL1ALDH1A1MAPK1 | |
| SCHEMBL16426683 | 0.77 | RAB9A (0.48) | IDO1MAPTL3MBTL1ALDH1A1MAPK1 | |
| SCHEMBL1146673 | 0.75 | APAF1 (0.37) | NR4A1MAPTL3MBTL1ALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2791252-A1 | TRIAROMATIC AZOMETHINE DIRECT DYES, DYE COMPOSITION COMPRISING AT LEAST ONE SUCH DYE, METHOD OF IMPLEMENTATION AND USE | L'OREAL (FR) | 2014-10-22 | — | — | EP | claimed |
| WO-2013087768-A1 | TRIAROMATIC AZOMETHINE DIRECT DYES, DYE COMPOSITION COMPRISING AT LEAST ONE SUCH DYE, METHOD OF IMPLEMENTATION AND USE | L'OREAL (FR) | 2013-06-20 | — | — | WO | claimed |
| US-9554977-B2 | Triaromatic azomethine direct dyes, dye composition comprising at least one such dye, method of implementation and use | L'OREAL (FR) | 2017-01-31 | — | — | US | disclosed |
| US-20150320660-A1 | TRIAROMATIC AZOMETHINE DIRECT DYES, DYE COMPOSITION COMPRISING AT LEAST ONE SUCH DYE, METHOD OF IMPLEMENTATION AND USE | L'OREAL (FR) | 2015-11-12 | — | — | US | disclosed |
| WO-2013087768-A1 | TRIAROMATIC AZOMETHINE DIRECT DYES, DYE COMPOSITION COMPRISING AT LEAST ONE SUCH DYE, METHOD OF IMPLEMENTATION AND USE | L'OREAL (FR) | 2013-06-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150320660-A1 | TRIAROMATIC AZOMETHINE DIRECT DYES, DYE COMPOSITION COMPRISING AT LEAST ONE SUCH DYE, METHOD OF IMPLEMENTATION AND USE | KRT18, MKI67, CDC73 | IDO1 238/4885NR4A1 2117/4885MAPT 469/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.