Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.35 |
| ▸ | APAF1 | O14727 | 6/20 | 0.35 |
| ▸ | HTT | P42858 | 6/20 | 0.35 |
| ▸ | MEN1 | O00255 | 6/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.35 |
| ▸ | HPGD | P15428 | 4/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
| ▸ | MITF | O75030 | 2/20 | 0.35 |
| ▸ | HKDC1 | Q2TB90 | 2/20 | 0.35 |
| ▸ | THRB | P10828 | 2/20 | 0.35 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.35 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.35 |
| ▸ | BLM | P54132 | 4/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.35 |
| ▸ | LMNA | P02545 | 4/20 | 0.35 |
| ▸ | NPC1 | O15118 | 4/20 | 0.35 |
| ▸ | RAB9A | P51151 | 4/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17253285 | 1.00 | MAPT (0.35) | MAPTKMT2AAPAF1HTTMEN1 | |
| SCHEMBL15020289 | 1.00 | MAPT (0.35) | MAPTKMT2AAPAF1HTTMEN1 | |
| SCHEMBL15019814 | 0.90 | APAF1 (0.39) | MAPTKMT2AAPAF1HTTMEN1 | |
| SCHEMBL15019813 | 0.90 | APAF1 (0.39) | MAPTKMT2AAPAF1HTTMEN1 | |
| SCHEMBL15039564 | 0.90 | APAF1 (0.39) | MAPTKMT2AAPAF1HTTMEN1 | |
| SCHEMBL17253269 | 0.90 | ALDH1A1 (0.37) | MAPTKMT2AAPAF1HTTMEN1 | |
| SCHEMBL15020129 | 0.90 | ALDH1A1 (0.37) | MAPTKMT2AAPAF1HTTMEN1 | |
| SCHEMBL15020128 | 0.90 | ALDH1A1 (0.37) | MAPTKMT2AAPAF1HTTMEN1 | |
| SCHEMBL15039548 | 0.88 | MAPT (0.41) | MAPTKMT2AAPAF1HTTMEN1 | |
| SCHEMBL15020117 | 0.85 | ALDH1A1 (0.35) | MAPTKMT2AAPAF1HTTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2791252-A1 | TRIAROMATIC AZOMETHINE DIRECT DYES, DYE COMPOSITION COMPRISING AT LEAST ONE SUCH DYE, METHOD OF IMPLEMENTATION AND USE | L'OREAL (FR) | 2014-10-22 | — | — | EP | claimed |
| WO-2013087768-A1 | TRIAROMATIC AZOMETHINE DIRECT DYES, DYE COMPOSITION COMPRISING AT LEAST ONE SUCH DYE, METHOD OF IMPLEMENTATION AND USE | L'OREAL (FR) | 2013-06-20 | — | — | WO | claimed |