Phthalimide

Phthalimide

SCHEMBL15020902

F.O=C1NC(=O)c2ccccc21

nearest known ligand 0.94

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ GSK3B P49841 1/20 0.94
▸ CASP7 P55210 3/20 0.75
▸ CASP3 P42574 2/20 0.75
▸ CASP6 P55212 2/20 0.75
▸ CASP8 Q14790 2/20 0.75
▸ CASP2 P42575 1/20 0.75
▸ PARP1 P09874 4/20 0.56
▸ PDGFRA P16234 1/20 0.56
▸ FER P16591 1/20 0.56
▸ LTK P29376 1/20 0.56
▸ CDK8 P49336 1/20 0.56
▸ ACVR1 Q04771 1/20 0.56
▸ LRRK2 Q5S007 1/20 0.56
▸ DYRK1B Q9Y463 1/20 0.56
▸ MAPK1 P28482 4/20 0.52
▸ LMNA P02545 3/20 0.52
▸ SMN1; SMN2 Q16637 3/20 0.52
▸ HSD17B10 Q99714 1/20 0.52
▸ MAOA P21397 5/20 0.50
▸ MAOB P27338 4/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phthalimide SCHEMBL29366030 0.97 GSK3B (1.00) GSK3BCASP7CASP3CASP6CASP8
Phthalimide SCHEMBL11040503 0.97 GSK3B (1.00) GSK3BCASP7CASP3CASP6CASP8
Phthalimide SCHEMBL10192661 0.97 GSK3B (1.00) GSK3BCASP7CASP3CASP6CASP8
Phthalimide SCHEMBL64 0.97 GSK3B (1.00) GSK3BCASP7CASP3CASP6CASP8
Phthalimide SCHEMBL30125197 0.97 GSK3B (1.00) GSK3BCASP7CASP3CASP6CASP8
Phthalimide SCHEMBL28226707 0.97 GSK3B (1.00) GSK3BCASP7CASP3CASP6CASP8
Phthalimide SCHEMBL7771670 0.97 GSK3B (1.00) GSK3BCASP7CASP3CASP6CASP8
Phthalimide SCHEMBL4297661 0.94 GSK3B (0.94) GSK3BCASP7CASP3CASP6CASP8
Phthalimide SCHEMBL7521027 0.94 GSK3B (0.94) GSK3BCASP7CASP3CASP6CASP8
Phthalimide SCHEMBL543800 0.94 GSK3B (0.94) GSK3BCASP7CASP3CASP6CASP8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2607416-B1 THERMOPLASTIC RESIN FOAM, METHOD OF PRODUCING THE SAME, AND LIGHT REFLECTING MATERIAL USING THE SAME FURUKAWA ELECTRIC CO LTD (JP) 2019-10-02 — — EP disclosed
US-8853288-B2 Thermoplastic resin foam, method of producing the same, and light reflecting material using the same FURUKAWA ELECTRIC CO., LTD. (JP) 2014-10-07 — — US disclosed
EP-2607416-A1 THERMOPLASTIC RESIN FOAM, PROCESS FOR PRODUCING THERMOPLASTIC RESIN FOAM, AND LIGHT REFLECTION MATERIAL Furukawa Electric Co., Ltd. (JP) 2013-06-26 — — EP disclosed
US-20130158143-A1 THERMOPLASTIC RESIN FOAM, METHOD OF PRODUCING THE SAME, AND LIGHT REFLECTING MATERIAL USING THE SAME FURUKAWA ELECTRIC CO., LTD. (JP) 2013-06-20 — — US disclosed
CN-101313246-A Radiation-sensitive resin composition JSR CORP (JP) 2008-11-26 — — CN disclosed
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