⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL142953 | 0.80 | — | — | |
| Bromide SCHEMBL8028729 | 0.78 | — | — | |
| SCHEMBL2148425 | 0.78 | — | — | |
| SCHEMBL2827736 | 0.65 | OPRM1 (0.31) | — | |
| SCHEMBL1069124 | 0.65 | — | — | |
| SCHEMBL3451559 | 0.64 | — | — | |
| SCHEMBL2775903 | 0.63 | — | — | |
| SCHEMBL22289366 | 0.62 | ADRB2 (0.36) | — | |
| SCHEMBL28387883 | 0.62 | OPRM1 (0.30) | — | |
| SCHEMBL6696793 | 0.62 | OPRM1 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10040969-B2 | Composite filler particles and process for the preparation thereof | DENTSPLY SIRONA INC. (US) | 2018-08-07 | — | — | US | disclosed |
| US-20160024334-A1 | COMPOSITE FILLER PARTICLES AND PROCESS FOR THE PREPARATION THEREOF | DENTSPLY INTERNATIONAL INC. (US) | 2016-01-28 | — | — | US | disclosed |
| US-9193849-B2 | Composite filler particles and process for the preparation thereof | DENTSPLY INTERNATIONAL INC. (US) | 2015-11-24 | — | — | US | disclosed |
| US-20130158157-A1 | COMPOSITE FILLER PARTICLES AND PROCESS FOR THE PREPARATION THEREOF | DENTSPLY INTERNATIONAL INC. (US) | 2013-06-20 | — | — | US | disclosed |